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Ensemble refinement of the protein crystal structure of gene product from Arabidopsis thaliana At5g06450

Source organism: Arabidopsis thaliana
Biochemical function: RISC complex binding
Biological process: positive regulation of miRNA metabolic process
Cellular component: cytoplasm

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EC 3.1.13.1: Exoribonuclease II

Reaction catalysed:
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Systematic name:
-
Alternative Name(s):
  • 5'-exoribonuclease
  • BN ribonuclease
  • Escherichia coli exo-RNase II
  • Exoribonuclease
  • RNase II
  • Ribonuclease II
  • Ribonuclease Q

GO terms

Sequence family

InterPro InterPro annotations
IPR012337
Domain description: Ribonuclease H-like superfamily
Occurring in:
  1. Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2
IPR036397
Domain description: Ribonuclease H superfamily
Occurring in:
  1. Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2

Structure domain

CATH CATH domain
3.30.420.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Ribonuclease H-like superfamily/Ribonuclease H
Occurring in:
  1. Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2
The deposited structure of PDB entry 2q3s contains 6 copies of CATH domain 3.30.420.10 (Nucleotidyltransferase; domain 5) in Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2. Showing 1 copy in chain A.
SCOP SCOP annotation
53118
Class: Alpha and beta proteins (a/b)
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Occurring in:
  1. Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2
The deposited structure of PDB entry 2q3s contains 6 copies of SCOP domain 53118 (DnaQ-like 3'-5' exonuclease) in Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2. Showing 1 copy in chain A.

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