Function and Biology

Karyopherin beta2/transportin

Source organism: Homo sapiens
Biochemical function: nuclear import signal receptor activity
Biological process: protein transport
Cellular component: extracellular exosome

Sequence families

Pfam Protein families (Pfam)
PF13513
Domain description: HEAT-like repeat
Occurring in:
  1. Transportin-1
The deposited structure of PDB entry 2qmr contains 4 copies of Pfam domain PF13513 (HEAT-like repeat) in Transportin-1. Showing 1 copy in chain A.

PF02985
Domain description: HEAT repeat
Occurring in:
  1. Transportin-1

PF03810
Domain description: Importin-beta N-terminal domain
Occurring in:
  1. Transportin-1
The deposited structure of PDB entry 2qmr contains 4 copies of Pfam domain PF03810 (Importin-beta N-terminal domain) in Transportin-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001494
Domain description: Importin-beta, N-terminal domain
Occurring in:
  1. Transportin-1
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Transportin-1
IPR040122
Domain description: Importin beta family
Occurring in:
  1. Transportin-1
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Transportin-1

Structure domain

CATH CATH domain
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Transportin-1
The deposited structure of PDB entry 2qmr contains 4 copies of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Transportin-1. Showing 1 copy in chain A.