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Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with benzylurea inhibitor CPBU

Source organism: Zea mays
Biochemical function: FAD binding
Biological process: cytokinin metabolic process
Cellular component: extracellular region

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EC 1.5.99.12: Cytokinin dehydrogenase

Reaction catalysed:
N(6)-prenyladenine + acceptor + H(2)O = adenine + 3-methylbut-2-enal + reduced acceptor
Systematic name:
N(6)-prenyladenine:acceptor oxidoreductase
Alternative Name(s):
  • 6-N-dimethylallyladenine:acceptor oxidoreductase
  • Cytokinin oxidase
  • N(6)-dimethylallyladenine:(acceptor) oxidoreductase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF09265
Domain description: Cytokinin dehydrogenase 1, FAD and cytokinin binding
Occurring in:
  1. Cytokinin dehydrogenase 1
The deposited structure of PDB entry 2qpm contains 1 copy of Pfam domain PF09265 (Cytokinin dehydrogenase 1, FAD and cytokinin binding) in Cytokinin dehydrogenase 1. Showing 1 copy in chain A.

PF01565
Domain description: FAD binding domain
Occurring in:
  1. Cytokinin dehydrogenase 1
The deposited structure of PDB entry 2qpm contains 1 copy of Pfam domain PF01565 (FAD binding domain) in Cytokinin dehydrogenase 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR016170
Domain description: Cytokinin dehydrogenase, C-terminal domain superfamily
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR016164
Domain description: FAD-linked oxidase-like, C-terminal
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR015345
Domain description: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR016169
Domain description: FAD-binding, type PCMH, subdomain 2
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR006094
Domain description: FAD linked oxidase, N-terminal
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR006093
Domain description: Oxygen oxidoreductase covalent FAD-binding site
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR016166
Domain description: FAD-binding domain, PCMH-type
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR016167
Domain description: FAD-binding, type PCMH, subdomain 1
Occurring in:
  1. Cytokinin dehydrogenase 1
IPR036318
Domain description: FAD-binding, type PCMH-like superfamily
Occurring in:
  1. Cytokinin dehydrogenase 1

Structure domains

CATH CATH domains
3.40.462.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Vanillyl-alcohol Oxidase; Chain A, domain 3
Homology: FAD-linked oxidases, C-terminal domain
Occurring in:
  1. Cytokinin dehydrogenase 1
The deposited structure of PDB entry 2qpm contains 1 copy of CATH domain 3.40.462.10 (Vanillyl-alcohol Oxidase; Chain A, domain 3) in Cytokinin dehydrogenase 1. Showing 1 copy in chain A.
3.30.43.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2
Homology: Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Occurring in:
  1. Cytokinin dehydrogenase 1
The deposited structure of PDB entry 2qpm contains 1 copy of CATH domain 3.30.43.10 (Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2) in Cytokinin dehydrogenase 1. Showing 1 copy in chain A.
3.30.465.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3
Homology: Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3
Occurring in:
  1. Cytokinin dehydrogenase 1
The deposited structure of PDB entry 2qpm contains 1 copy of CATH domain 3.30.465.10 (Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3) in Cytokinin dehydrogenase 1. Showing 1 copy in chain A.

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