› 2r51

X-ray diffraction
2.1Å resolution

Crystal Structure of mouse Vps26B

Released:
DOI: 10.2210/pdb2r51/pdb
PDB entry 2r51 coloured by chain, front view.
PDB entry 2r51 coloured by chain, side view.
PDB entry 2r51 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of Vps26B and mapping of its interaction with the retromer protein complex.
Collins BM, Norwood SJ, Kerr MC, Mahony D, Seaman MN, Teasdale RD, Owen DJ
Traffic 9 366-79 (2008)
PMID: 18088321

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-183926 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 26B Chain: A
Molecule details ›
Chain: A
Length: 340 amino acids
Theoretical weight: 40.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8C0E2 (Residues: 7-336; Coverage: 98%)
Gene name: Vps26b
Sequence domains: Vacuolar protein sorting-associated protein 26
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I212121
Unit cell:
a: 90.755Å b: 125.047Å c: 99.896Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.194 0.24
Expression system: Escherichia coli

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Citations

24 review citations

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.
Sugiura et al. (2014)
23 more

4 mentions without citation

Discovery of new GPCR biology: one receptor structure at a time.
Hanson et al. (2009)
3 more