EC 6.5.1.1: DNA ligase (ATP)
Reaction catalysed:
(1a) ATP + [DNA ligase]-L-lysine = [DNA ligase]-N(6)-(5'-adenylyl)-L-lysine + diphosphate
Systematic name:
Poly(deoxyribonucleotide)-3'-hydroxyl:5'-phospho-poly(deoxyribonucleotide) ligase (ATP)
Alternative Name(s):
- DNA joinase
- DNA ligase
- DNA repair enzyme
- DNA-joining enzyme
- Deoxyribonucleate ligase
- Deoxyribonucleic acid joinase
- Deoxyribonucleic acid ligase
- Deoxyribonucleic acid repair enzyme
- Deoxyribonucleic acid-joining enzyme
- Deoxyribonucleic joinase
- Deoxyribonucleic ligase
- Deoxyribonucleic repair enzyme
- Deoxyribonucleic-joining enzyme
- Poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)
- Polydeoxyribonucleotide synthase (ATP)
- Polynucleotide ligase
- Polynucleotide ligase (ATP)
- Sealase
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Protein family (Pfam)
InterPro annotations
CATH domain![The deposited structure of PDB entry 2r9l contains 2 copies of CATH domain 3.30.70.3300 (Alpha-Beta Plaits) in Multifunctional non-homologous end joining DNA repair protein LigD. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/2r9l_4_A_CATH_3.30.70.3300_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2r9l</span> contains 2 copies of CATH domain <span class='highlight'>3.30.70.3300 (Alpha-Beta Plaits)</span> in <span class='highlight'>Multifunctional non-homologous end joining DNA repair protein LigD</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")