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The PX-BAR membrane remodeling unit of Sorting Nexin 9

Source organism: Homo sapiens
Biochemical function: phosphatidylinositol binding
Biological process: endocytosis
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF10456
Domain description: WASP-binding domain of Sorting nexin protein
Occurring in:
  1. Sorting nexin-9
The deposited structure of PDB entry 2rai contains 2 copies of Pfam domain PF10456 (WASP-binding domain of Sorting nexin protein) in Sorting nexin-9. Showing 1 copy in chain B.

PF00787
Domain description: PX domain
Occurring in:
  1. Sorting nexin-9
The deposited structure of PDB entry 2rai contains 2 copies of Pfam domain PF00787 (PX domain) in Sorting nexin-9. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001683
Domain description: Phox homology
Occurring in:
  1. Sorting nexin-9
IPR027267
Domain description: AH/BAR domain superfamily
Occurring in:
  1. Sorting nexin-9
IPR036871
Domain description: PX domain superfamily
Occurring in:
  1. Sorting nexin-9
IPR037425
Domain description: Sorting nexin-9, BAR domain
Occurring in:
  1. Sorting nexin-9
IPR019497
Domain description: Sorting nexin protein, WASP-binding domain
Occurring in:
  1. Sorting nexin-9
IPR037426
Domain description: Sorting nexin-9, PX domain
Occurring in:
  1. Sorting nexin-9

Structure domains

CATH CATH domains
1.20.1270.60
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Substrate Binding Domain Of Dnak; Chain:A; Domain 2
Homology: Arfaptin homology (AH) domain/BAR domain
Occurring in:
  1. Sorting nexin-9
The deposited structure of PDB entry 2rai contains 2 copies of CATH domain 1.20.1270.60 (Substrate Binding Domain Of Dnak; Chain:A; Domain 2) in Sorting nexin-9. Showing 1 copy in chain B.
3.30.1520.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: PX Domain
Homology: Phox-like domain
Occurring in:
  1. Sorting nexin-9
The deposited structure of PDB entry 2rai contains 2 copies of CATH domain 3.30.1520.10 (PX Domain) in Sorting nexin-9. Showing 1 copy in chain B.

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