› 2rca

X-ray diffraction
1.58Å resolution

Crystal structure of the NR3B ligand binding core complex with glycine at 1.58 Angstrom resolution

Released:
DOI: 10.2210/pdb2rca/pdb
PDB entry 2rca coloured by chain, front view.
PDB entry 2rca coloured by chain, side view.
PDB entry 2rca coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
Yao Y, Harrison CB, Freddolino PL, Schulten K, Mayer ML
EMBO J 27 2158-70 (2008)
PMID: 18636091

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186587 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, NMDA 3B Chains: A, B
Molecule details ›
Chains: A, B
Length: 292 amino acids
Theoretical weight: 32.18 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8VHN2 (Residues: 413-815; Coverage: 30%)
Gene name: Grin3b
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand GLY 2 x GLY
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 45.915Å b: 83.597Å c: 145.153Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.192 0.231
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Glutamate receptor ion channels: structure, regulation, and function.
Traynelis et al. (2010)
18 more

3 mentions without citation

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
2 more