› 2rvk

Solution NMR

Refined solution structure of Schizosaccharomyces pombe Sin1 CRIM domain

Released:
DOI: 10.2210/pdb2rvk/pdb
PDB entry 2rvk coloured by chain, ensemble of 10 models, front view.
PDB entry 2rvk coloured by chain, ensemble of 10 models, side view.
PDB entry 2rvk coloured by chain, ensemble of 10 models, top view.
Source organism: Schizosaccharomyces pombe 972h-
Primary publication:
Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.
Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K
OpenAccess logo Elife 6 (2017)
PMID: 28264193

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Target of rapamycin complex 2 subunit sin1 Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 17.59 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P7Y9 (Residues: 247-400; Coverage: 23%)
Gene names: SPAPYUG7.02c, sin1
Sequence domains: SAPK-interacting protein 1 (Sin1), middle CRIM domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Homing in: Mechanisms of Substrate Targeting by Protein Kinases.
Miller et al. (2018)
16 more

5 mentions without citation

Protein kinase C: release from quarantine by mTORC2.
Baffi et al. (2022)
4 more