Function and Biology

THE THREE-DIMENSIONAL STRUCTURE OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI COMPLEXED WITH ADP

Source organism: Dickeya chrysanthemi
Biochemical function: metal ion binding
Biological process: carboxylic acid metabolic process
Cellular component: cytosol

EC 2.7.1.71: Shikimate kinase

Reaction catalysed:
ATP + shikimate = ADP + shikimate 3-phosphate
Systematic name:
ATP:shikimate 3-phosphotransferase
Alternative Name(s):
  • Shikimate kinase (phosphorylating)
  • Shikimate kinase II

Sequence family

Pfam Protein family (Pfam)
PF01202
Domain description: Shikimate kinase
Occurring in:
  1. Shikimate kinase 2
The deposited structure of PDB entry 2shk contains 2 copies of Pfam domain PF01202 (Shikimate kinase) in Shikimate kinase 2. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000623
Domain description: Shikimate kinase/Threonine synthase-like 1
Occurring in:
  1. Shikimate kinase 2
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Shikimate kinase 2
IPR023000
Domain description: Shikimate kinase, conserved site
Occurring in:
  1. Shikimate kinase 2
IPR031322
Domain description: Shikimate kinase/gluconokinase
Occurring in:
  1. Shikimate kinase 2
IPR027544
Domain description: Shikimate kinase 2
Occurring in:
  1. Shikimate kinase 2

Structure domain

CATH CATH domain
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Shikimate kinase 2
The deposited structure of PDB entry 2shk contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in Shikimate kinase 2. Showing 1 copy in chain B.
SCOP SCOP annotation
52566
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Shikimate kinase 2
The deposited structure of PDB entry 2shk contains 2 copies of SCOP domain 52566 (Shikimate kinase (AroK)) in Shikimate kinase 2. Showing 1 copy in chain B.