› › Structure analysis

LEUCINE-272-ALANINE URACIL-DNA GLYCOSYLASE BOUND TO ABASIC SITE-CONTAINING DNA

X-ray diffraction
2.25Å resolution
PDB entry 2ssp coloured by chain, front view.
PDB entry 2ssp coloured by chain, side view.
PDB entry 2ssp coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Uracil-DNA glycosylase and DNA
hide full assembly name
Multimeric state: hetero trimer
Accessible surface area: 12698.17 Å2
Buried surface area: 2712.94 Å2
Dissociation area: 1,260.07 Å2
Dissociation energy (ΔGdiss): 3.33 kcal/mol
Dissociation entropy (TΔSdiss): 19.45 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-115847

Macromolecules

Uracil-DNA glycosylase
Chain: E
Length: 223 amino acids
Theoretical weight: 25.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13051 (Residues: 94-313; Coverage: 70%)
Gene names: DGU, UNG, UNG1, UNG15
Pfam: Uracil DNA glycosylase superfamily
InterPro:
CATH: Uracil-DNA glycosylase-like domain
SCOP: Uracil-DNA glycosylase
Uracil-DNA glycosylase in PDB entry 2ssp, assembly 1, front view.
Uracil-DNA glycosylase in PDB entry 2ssp, assembly 1, side view.
Uracil-DNA glycosylase in PDB entry 2ssp, assembly 1, top view.
Molecule details ›

Search similar proteins

DNA chain A
Name: DNA (5'-D(*CP*TP*GP*TP*(AAB)P*AP*TP*CP*TP*T)-3')
Representative chains: A
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 10 nucleotides
Theoretical weight: 2.89 KDa
DNA (5'-D(*CP*TP*GP*TP*(AAB)P*AP*TP*CP*TP*T)-3') in PDB entry 2ssp, assembly 1, front view.
DNA (5'-D(*CP*TP*GP*TP*(AAB)P*AP*TP*CP*TP*T)-3') in PDB entry 2ssp, assembly 1, side view.
DNA (5'-D(*CP*TP*GP*TP*(AAB)P*AP*TP*CP*TP*T)-3') in PDB entry 2ssp, assembly 1, top view.
Molecule details ›

Search similar DNA

DNA chain B
Name: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3')
Representative chains: B
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 11 nucleotides
Theoretical weight: 3.4 KDa
DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3') in PDB entry 2ssp, assembly 1, front view.
DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3') in PDB entry 2ssp, assembly 1, side view.
DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3') in PDB entry 2ssp, assembly 1, top view.
Molecule details ›

Search similar DNA

Quick links