Function and Biology

Structure of a family 26 lichenase in complex with noeuromycin

Source organism: Acetivibrio thermocellus
Biochemical function: mannan endo-1,4-beta-mannosidase activity
Biological process: substituted mannan metabolic process
Cellular component: not assigned

EC 3.2.1.4: Cellulase

Reaction catalysed:
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
Systematic name:
4-beta-D-glucan 4-glucanohydrolase
Alternative Name(s):
  • 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase
  • 9.5 cellulase
  • Alkali cellulase
  • Avicelase
  • Beta-1,4-endoglucan hydrolase
  • Beta-1,4-glucanase
  • Carboxymethyl cellulase
  • Celluase A
  • Celludextrinase
  • Cellulase A 3
  • Cellulosin AP
  • Endo-1,4-beta-D-glucanase
  • Endo-1,4-beta-D-glucanohydrolase
  • Endo-1,4-beta-glucanase
  • Endoglucanase
  • Endoglucanase D
  • Pancellase SS

GO terms

Sequence family

Pfam Protein family (Pfam)
PF02156
Domain description: Glycosyl hydrolase family 26
Occurring in:
  1. Endoglucanase H
The deposited structure of PDB entry 2v3g contains 1 copy of Pfam domain PF02156 (Glycosyl hydrolase family 26) in Endoglucanase H. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR022790
Domain description: Glycosyl hydrolase family 26 domain
Occurring in:
  1. Endoglucanase H
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Endoglucanase H
IPR000805
Domain description: Glycoside hydrolase family 26
Occurring in:
  1. Endoglucanase H

Structure domain

CATH CATH domain
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Endoglucanase H
The deposited structure of PDB entry 2v3g contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Endoglucanase H. Showing 1 copy in chain A.
SCOP SCOP annotation
51487
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Occurring in:
  1. Endoglucanase H
The deposited structure of PDB entry 2v3g contains 1 copy of SCOP domain 51487 (beta-glycanases) in Endoglucanase H. Showing 1 copy in chain A.