› 2v5t

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 2 Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.15 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: O15394 (Residues: 115-301; Coverage: 23%)
Gene names: NCAM2, NCAM21
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand NAG 2 x NAG
Ligand GOL 4 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P41212
Unit cell:
a: 114.95Å b: 114.95Å c: 46Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.181 0.234
Expression system: Komagataella pastoris

Quick links

Citations

6 review citations

Polysialic acid: biosynthesis, novel functions and applications.
Colley et al. (2014)
5 more

2 mentions without citation

Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies.
Elorza-Vidal et al. (2020)
1 more