› 2v94

X-ray diffraction
1.9Å resolution

Crystal structure of P. abyssi RPS24

Released:
DOI: 10.2210/pdb2v94/pdb
PDB entry 2v94 coloured by chain, front view.
PDB entry 2v94 coloured by chain, side view.
PDB entry 2v94 coloured by chain, top view.
Source organism: Pyrococcus abyssi
Primary publication:
Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder.
Choesmel V, Fribourg S, Aguissa-Touré AH, Pinaud N, Legrand P, Gazda HT, Gleizes PE
Hum Mol Genet 17 1253-63 (2008)
PMID: 18230666

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small ribosomal subunit protein eS24 Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 13.03 KDa
Source organism: Pyrococcus abyssi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UY20 (Residues: 1-99; Coverage: 100%)
Gene names: PAB3419, PYRAB16880, rps24e
Sequence domains: Ribosomal protein S24e
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21212
Unit cell:
a: 66.81Å b: 85.63Å c: 42.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.266
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Ribosomopathies: human disorders of ribosome dysfunction.
Narla et al. (2010)
25 more