› 2vbi

X-ray diffraction
2.75Å resolution

Holostructure of pyruvate decarboxylase from Acetobacter pasteurianus

Released:
DOI: 10.2210/pdb2vbi/pdb
PDB entry 2vbi coloured by chain, front view.
PDB entry 2vbi coloured by chain, side view.
PDB entry 2vbi coloured by chain, top view.
Source organism: Acetobacter pasteurianus
Entry authors: Gocke D, Berthold CL, Schneider G, Pohl M

Function and Biology Details

Reaction catalysed: 
A 2-oxo acid = an aldehyde + CO(2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185243 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
pyruvate decarboxylase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 566 amino acids
Theoretical weight: 61.19 KDa
Source organism: Acetobacter pasteurianus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8L388 (Residues: 1-397, 398-557; Coverage: 100%)
Gene name: pdc
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand TPP 8 x TPP
1 bound ligand:
Ligand MG 8 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: C2
Unit cell:
a: 179.619Å b: 162.434Å c: 169.331Å
α: 90° β: 102.71° γ: 90°
R-values:
R R work R free
0.225 0.224 0.243
Expression system: Escherichia coli BL21(DE3)

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