Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
A 5'-triphospho-[mRNA] + H(2)O = a 5'-diphospho-[mRNA] + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
mRNA-capping enzyme (preferred)
PDBe Complex ID:
PDB-CPX-137587 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
mRNA-capping enzyme catalytic subunit
Molecule details ›
Chains: A, C, E, G
Length: 302 amino acids
Theoretical weight: 34.76 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: mRNA (guanine-N(7))-methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Length: 302 amino acids
Theoretical weight: 34.76 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P04298 (Residues: 545-844; Coverage: 36%)
Sequence domains: mRNA (guanine-N(7))-methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
mRNA-capping enzyme regulatory subunit OPG124
Molecule details ›
Chains: B, D, F, H
Length: 287 amino acids
Theoretical weight: 33.4 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Poxvirus mRNA capping enzyme, small subunit
Structure domains: Poxvirus mRNA capping enzyme, small subunit
Length: 287 amino acids
Theoretical weight: 33.4 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04318 (Residues: 1-287; Coverage: 100%)
Sequence domains: Poxvirus mRNA capping enzyme, small subunit
Structure domains: Poxvirus mRNA capping enzyme, small subunit
