› 2vfk

X-ray diffraction
1.5Å resolution

AKAP18 delta central domain - AMP

Released:
DOI: 10.2210/pdb2vfk/pdb
PDB entry 2vfk coloured by chain, front view.
PDB entry 2vfk coloured by chain, side view.
PDB entry 2vfk coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
AKAP18 contains a phosphoesterase domain that binds AMP.
Gold MG, Smith FD, Scott JD, Barford D
J Mol Biol 375 1329-43 (2008)
PMID: 18082768

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163265 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AKAP18 DELTA Chain: A
Molecule details ›
Chain: A
Length: 205 amino acids
Theoretical weight: 23.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
Structure domains: Cyclic phosphodiesterase

Ligands and Environments

1 bound ligand:
Ligand AMP 1 x AMP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P31
Unit cell:
a: 42.233Å b: 42.233Å c: 97.723Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.163 0.161 0.209
Expression system: Escherichia coli BL21

Quick links

Citations

7 review citations

Creating order from chaos: cellular regulation by kinase anchoring.
Scott et al. (2013)
6 more

14 mentions without citation

Molecular Evolution of Human Coronavirus Genomes.
Forni et al. (2017)
13 more