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Human Notch-1 EGFs 11-13

Source organism: Homo sapiens
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00008
Domain description: EGF-like domain
Occurring in:
  1. Neurogenic locus notch homolog protein 1
The deposited structure of PDB entry 2vj3 contains 2 copies of Pfam domain PF00008 (EGF-like domain) in Neurogenic locus notch homolog protein 1. Showing 2 copies in chain A.

PF07645
Domain description: Calcium-binding EGF domain
Occurring in:
  1. Neurogenic locus notch homolog protein 1
The deposited structure of PDB entry 2vj3 contains 1 copy of Pfam domain PF07645 (Calcium-binding EGF domain) in Neurogenic locus notch homolog protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000742
Domain description: EGF-like domain
Occurring in:
  1. Neurogenic locus notch homolog protein 1
IPR001881
Domain description: EGF-like calcium-binding domain
Occurring in:
  1. Neurogenic locus notch homolog protein 1
IPR000152
Domain description: EGF-type aspartate/asparagine hydroxylation site
Occurring in:
  1. Neurogenic locus notch homolog protein 1
IPR018097
Domain description: EGF-like calcium-binding, conserved site
Occurring in:
  1. Neurogenic locus notch homolog protein 1
IPR009030
Domain description: Growth factor receptor cysteine-rich domain superfamily
Occurring in:
  1. Neurogenic locus notch homolog protein 1

Structure domain

CATH CATH domain
2.10.25.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Laminin
Homology: Laminin
Occurring in:
  1. Neurogenic locus notch homolog protein 1
The deposited structure of PDB entry 2vj3 contains 3 copies of CATH domain 2.10.25.10 (Laminin) in Neurogenic locus notch homolog protein 1. Showing 3 copies in chain A.
SCOP SCOP annotation
57197
Class: Small proteins
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: EGF/Laminin
Occurring in:
  1. Neurogenic locus notch homolog protein 1
The deposited structure of PDB entry 2vj3 contains 3 copies of SCOP domain 57197 (EGF-type module) in Neurogenic locus notch homolog protein 1. Showing 3 copies in chain A.

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