› 2vjq

X-ray diffraction
1.8Å resolution

Function and Biology Details

Reaction catalysed: 
Formyl-CoA + oxalate = formate + oxalyl-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formyl-CoA:oxalate CoA-transferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 428 amino acids
Theoretical weight: 47.3 KDa
Source organism: Oxalobacter formigenes
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O06644 (Residues: 1-428; Coverage: 100%)
Gene name: frc
Sequence domains: CoA-transferase family III
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EPE 2 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 214.155Å b: 98.917Å c: 152.527Å
α: 90° β: 135.27° γ: 90°
R-values:
R R work R free
0.182 0.181 0.212
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Probiotics in the Prevention of the Calcium Oxalate Urolithiasis.
Wigner et al. (2022)
13 other articles

2 mentions without citation

Differential substrate specificity and kinetic behavior of Escherichia coli YfdW and Oxalobacter formigenes formyl coenzyme A transferase.
Toyota et al. (2008)
1 more