› 2vy3

X-ray diffraction
2.8Å resolution

Type IV secretion system effector protein BepA

Released:
DOI: 10.2210/pdb2vy3/pdb
PDB entry 2vy3 coloured by chain, front view.
PDB entry 2vy3 coloured by chain, side view.
PDB entry 2vy3 coloured by chain, top view.
Source organism: Bartonella henselae
Primary publication:
Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA.
Palanivelu DV, Goepfert A, Meury M, Guye P, Dehio C, Schirmer T
Protein Sci 20 492-9 (2011)
PMID: 21213248

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein adenylyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 302 amino acids
Theoretical weight: 34.85 KDa
Source organism: Bartonella henselae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6G2A9 (Residues: 1-302; Coverage: 56%)
Gene names: BH13370, bepA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NI 4 x NI
Ligand CL 2 x CL
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 73.336Å b: 84.61Å c: 126.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.216 0.276
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Intruders below the radar: molecular pathogenesis of Bartonella spp.
Harms et al. (2012)
12 more

2 mentions without citation

Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA.
Palanivelu et al. (2011)
1 more