› 2w5p

X-ray diffraction
1.9Å resolution

DraE Adhesin in complex with Chloramphenicol Succinate (monoclinic form)

Released:
DOI: 10.2210/pdb2w5p/pdb
PDB entry 2w5p coloured by chain, front view.
PDB entry 2w5p coloured by chain, side view.
PDB entry 2w5p coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Pettigrew DM, Roversi P, Davies SG, Russell AJ, Lea SM
OpenAccess logo Acta Crystallogr D Biol Crystallogr 65 513-22 (2009)
PMID: 19465765

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150156 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dr hemagglutinin structural subunit Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 149 amino acids
Theoretical weight: 16.17 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P24093 (Residues: 20-160; Coverage: 100%)
Gene name: draA
Sequence domains: Dr-family adhesin
Structure domains: Dr adhesin

Ligands and Environments

2 bound ligands:
Ligand CL8 3 x CL8
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: C2
Unit cell:
a: 118.941Å b: 68.553Å c: 62.061Å
α: 90° β: 111.17° γ: 90°
R-values:
R R work R free
0.195 0.193 0.237
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint.
Zav'yalov et al. (2010)
2 more

2 mentions without citation

A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Pettigrew et al. (2009)
1 more