EC 5.3.1.16: 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
Reaction catalysed:
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D-ribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino)-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide
Systematic name:
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D-ribosylamino)methylideneamino)imidazole-4-carboxamide aldose-ketose-isomerase
Alternative Name(s):
- 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide ketol-isomerase
- N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase
- N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase
- Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
- Phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase
Protein family (Pfam)![The deposited structure of PDB entry 2w79 contains 2 copies of Pfam domain PF00977 (Histidine biosynthesis protein) in 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/2w79_1_A_Pfam_PF00977_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2w79</span> contains 2 copies of Pfam domain <span class='highlight'>PF00977 (Histidine biosynthesis protein)</span> in <span class='highlight'>1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 2w79 contains 2 copies of CATH domain 3.20.20.70 (TIM Barrel) in 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/2w79_1_A_CATH_3.20.20.70_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2w79</span> contains 2 copies of CATH domain <span class='highlight'>3.20.20.70 (TIM Barrel)</span> in <span class='highlight'>1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")