Function and Biology Details
Reaction catalysed:
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- 6-phosphogluconate dehydrogenase
- 6-phosphogluconate dehydrogenase, C-terminal
- 6-phosphogluconate dehydrogenase, decarboxylating
- 6-phosphogluconate-binding site
- 6-phosphogluconate dehydrogenase, domain 2
- 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
- 6-phosphogluconate dehydrogenase, NADP-binding
- NAD(P)-binding domain superfamily
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-516041 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-phosphogluconate dehydrogenase, decarboxylating
Molecule details ›
Chains: A, B
Length: 470 amino acids
Theoretical weight: 52.14 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 470 amino acids
Theoretical weight: 52.14 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
I3NI58 (Residues: 1-470; Coverage: 100%)
- NAD binding domain of 6-phosphogluconate dehydrogenase
- 6-phosphogluconate dehydrogenase, C-terminal domain
