2xr6

X-ray diffraction
1.35Å resolution

Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192443 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD209 antigen Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 19.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NNX6 (Residues: 250-404; Coverage: 38%)
Gene names: CD209, CLEC4L
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P43212
Unit cell:
a: 71.33Å b: 71.33Å c: 52.666Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.148 0.147 0.168
Expression system: Escherichia coli BL21(DE3)