Function and Biology Details
Reactions catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Zinc finger, RING-type
- SH2 domain superfamily
- Adaptor protein Cbl, SH2-like domain
- Adaptor protein Cbl, N-terminal domain superfamily
- Zinc finger, RING-type, conserved site
- E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass
- Zinc finger, RING/FYVE/PHD-type
- Adaptor protein Cbl, EF hand-like
4 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149757 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):