Function and Biology

WIF domain-epidermal growth factor (EGF)-like domains 1-3 of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF12661
Domain description: Human growth factor-like EGF
Occurring in:
  1. Wnt inhibitory factor 1
The deposited structure of PDB entry 2ygq contains 5 copies of Pfam domain PF12661 (Human growth factor-like EGF) in Wnt inhibitory factor 1. Showing 5 copies in chain A (some of the copies are out of the observed residue ranges!).

PF02019
Domain description: WIF domain
Occurring in:
  1. Wnt inhibitory factor 1
The deposited structure of PDB entry 2ygq contains 1 copy of Pfam domain PF02019 (WIF domain) in Wnt inhibitory factor 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000742
Domain description: EGF-like domain
Occurring in:
  1. Wnt inhibitory factor 1
IPR013309
Domain description: Wnt inhibitory factor (WIF)-1
Occurring in:
  1. Wnt inhibitory factor 1
IPR003306
Domain description: WIF domain
Occurring in:
  1. Wnt inhibitory factor 1
IPR013032
Domain description: EGF-like, conserved site
Occurring in:
  1. Wnt inhibitory factor 1
IPR038677
Domain description: WIF domain superfamily
Occurring in:
  1. Wnt inhibitory factor 1

Structure domains

CATH CATH domains
2.10.25.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Laminin
Homology: Laminin
Occurring in:
  1. Wnt inhibitory factor 1
The deposited structure of PDB entry 2ygq contains 1 copy of CATH domain 2.10.25.10 (Laminin) in Wnt inhibitory factor 1. Showing 1 copy in chain A.
2.60.40.2170
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Wnt, WIF domain
Occurring in:
  1. Wnt inhibitory factor 1
The deposited structure of PDB entry 2ygq contains 1 copy of CATH domain 2.60.40.2170 (Immunoglobulin-like) in Wnt inhibitory factor 1. Showing 1 copy in chain A.