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Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: mRNA processing
Cellular component: nucleus

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00076
Domain description: RNA recognition motif
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit
The deposited structure of PDB entry 2yh0 contains 2 copies of Pfam domain PF00076 (RNA recognition motif) in Splicing factor U2AF 65 kDa subunit. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit
IPR006529
Domain description: U2 snRNP auxilliary factor, large subunit, splicing factor
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit

Structure domain

CATH CATH domain
3.30.70.330
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. Splicing factor U2AF 65 kDa subunit
The deposited structure of PDB entry 2yh0 contains 2 copies of CATH domain 3.30.70.330 (Alpha-Beta Plaits) in Splicing factor U2AF 65 kDa subunit. Showing 2 copies in chain A.

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