› 2z5e

X-ray diffraction
2Å resolution

Crystal Structure of Proteasome Assembling Chaperone 3

Released:
DOI: 10.2210/pdb2z5e/pdb
PDB entry 2z5e coloured by chain, front view.
PDB entry 2z5e coloured by chain, side view.
PDB entry 2z5e coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes.
Yashiroda H, Mizushima T, Okamoto K, Kameyama T, Hayashi H, Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K, Suzuki A, Hirano Y, Murata S, Kato K, Yamane T, Tanaka K
Nat Struct Mol Biol 15 228-36 (2008)
PMID: 18278057

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-573505 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome assembly chaperone 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 122 amino acids
Theoretical weight: 13.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BT73 (Residues: 1-122; Coverage: 100%)
Gene names: C7orf48, PAC3, PSMG3
Sequence domains: Proteasome assembly chaperone 3
Structure domains: Ribosomal Protein S5; domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 88.642Å b: 88.642Å c: 57.179Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.18 0.252
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

30 review citations

The proteasome: overview of structure and functions.
Tanaka K. (2009)
29 more

3 mentions without citation

Molecular and Structural Basis of the Proteasome α Subunit Assembly Mechanism Mediated by the Proteasome-Assembling Chaperone PAC3-PAC4 Heterodimer.
Satoh et al. (2019)
2 more