› 3c07

X-ray diffraction
2.7Å resolution

Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)

Released:
DOI: 10.2210/pdb3c07/pdb
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PDB entry 3c07 coloured by chain, front view.
PDB entry 3c07 coloured by chain, side view.
PDB entry 3c07 coloured by chain, top view.
Source organism: Streptomyces coelicolor A3(2)
Entry authors: Tan K, Xu X, Zheng H, Savchenko A, Edwards AM, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 273 amino acids
Theoretical weight: 31.26 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9KZ96 (Residues: 1-251; Coverage: 100%)
Gene names: SC5G8.18c, SCO4850
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 74.947Å b: 74.947Å c: 208.075Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.218 0.289
Expression system: Escherichia coli BL21

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