Function and Biology Details
Reaction catalysed:
ATP + H(2)O + cellular protein(Side 1) = ADP + phosphate + cellular protein(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Protein translocase subunit SecA
- Preprotein translocase SecG subunit
- SecE subunit of protein translocation complex, bacterial-like
- P-loop containing nucleoside triphosphate hydrolase
- SecY/SEC61-alpha family
- SecY conserved site
- SecY domain superfamily
- Protein translocase complex, SecE/Sec61-gamma subunit
12 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-112102 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Protein translocase subunit SecA
Molecule details ›
Chains: A, B
Length: 779 amino acids
Theoretical weight: 88.8 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 779 amino acids
Theoretical weight: 88.8 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
- Canonical:
P28366 (Residues: 1-779; Coverage: 93%)
Sequence domains:
Protein translocase subunit SecY
Molecule details ›
Chains: G, H
Length: 429 amino acids
Theoretical weight: 48.14 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
Sequence domains: SecY
Length: 429 amino acids
Theoretical weight: 48.14 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
- Canonical: O66491 (Residues: 1-429; Coverage: 100%)
Sequence domains: SecY
Protein translocase subunit SecE
Protein-export membrane protein SecG
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
P212121
Expression system: Escherichia coli
