› 3fs7

X-ray diffraction
1.95Å resolution

Crystal structure of Gallus gallus beta-parvalbumin (avian thymic hormone)

Released:
DOI: 10.2210/pdb3fs7/pdb
PDB entry 3fs7 coloured by chain, front view.
PDB entry 3fs7 coloured by chain, side view.
PDB entry 3fs7 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structure of avian thymic hormone, a high-affinity avian beta-parvalbumin, in the Ca2+-free and Ca2+-bound states.
Schuermann JP, Tan A, Tanner JJ, Henzl MT
J Mol Biol 397 991-1002 (2010)
PMID: 20156445

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148706 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parvalbumin, thymic Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 109 amino acids
Theoretical weight: 11.74 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19753 (Residues: 1-109; Coverage: 100%)
Sequence domains: EF-hand domain
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:
Ligand CA 16 x CA
Ligand SO4 4 x SO4
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P1
Unit cell:
a: 47.644Å b: 51.56Å c: 67.633Å
α: 87.42° β: 85.42° γ: 87.42°
R-values:
R R work R free
0.166 0.164 0.221
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 citation in other articles

Solution structures of chicken parvalbumin 3 in the Ca(2+)-free and Ca(2+)-bound states.
Henzl et al. (2011)
2 more

3 mentions without citation

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.
Tyagi et al. (2015)
2 more