› 3ft1

X-ray diffraction
1.79Å resolution

Crystal structure of pollen allergen Phl p 3

Released:
DOI: 10.2210/pdb3ft1/pdb
PDB entry 3ft1 coloured by chain, front view.
PDB entry 3ft1 coloured by chain, side view.
PDB entry 3ft1 coloured by chain, top view.
Source organism: Phleum pratense
Primary publication:
High-resolution crystal structure and IgE recognition of the major grass pollen allergen Phl p 3.
Devanaboyina SC, Cornelius C, Lupinek C, Fauland K, Dall'Antonia F, Nandy A, Hagen S, Flicker S, Valenta R, Keller W
Allergy 69 1617-28 (2014)
PMID: 25123586

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179374 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Expansin-like CBD domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 100 amino acids
Theoretical weight: 11.38 KDa
Source organism: Phleum pratense
Expression system: Escherichia coli
UniProt:
  • Canonical: Q69B42 (Residues: 1-97; Coverage: 100%)
Sequence domains: Expansin C-terminal domain
Structure domains: Expansin, cellulose-binding-like domain

Ligands and Environments

1 bound ligand:
Ligand CL 10 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P21
Unit cell:
a: 46.068Å b: 74.447Å c: 56.693Å
α: 90° β: 104.59° γ: 90°
R-values:
R R work R free
0.17 0.17 0.222
Expression system: Escherichia coli

Quick links

Citations

7 review citations

WHO/IUIS Allergen Nomenclature: Providing a common language.
Pomés et al. (2018)
6 more

3 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
2 more