3h9v

X-ray diffraction
3.1Å resolution

Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms

Released:
Source organism: Danio rerio

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
P2X purinoceptor 4a Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.3 KDa
Source organism: Danio rerio
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: F8W463 (Residues: 28-381; Coverage: 91%)
Gene name: p2rx4a
Sequence domains: ATP P2X receptor
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: R32
Unit cell:
a: 100.836Å b: 100.836Å c: 431.316Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.249 0.248 0.278
Expression system: Spodoptera frugiperda