› 3ivf

X-ray diffraction
1.94Å resolution

Crystal structure of the talin head FERM domain

Released:
DOI: 10.2210/pdb3ivf/pdb
PDB entry 3ivf coloured by chain, front view.
PDB entry 3ivf coloured by chain, side view.
PDB entry 3ivf coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The Structure of the talin head reveals a novel extended conformation of the FERM domain.
Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL
OpenAccess logo Structure 18 1289-99 (2010)
PMID: 20947018

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 42.93 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26039 (Residues: 1-400; Coverage: 15%)
Gene names: Tln, Tln1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Unit cell:
a: 40.26Å b: 72.16Å c: 162.83Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.193 0.257
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Talins and kindlins: partners in integrin-mediated adhesion.
Calderwood et al. (2013)
28 more

26 mentions without citation

Reconstruction of integrin activation.
Ye et al. (2012)
25 more