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Electron Microscopy
28Å resolution

Crystal structure of mTOR docked into EM map of dimeric ATM kinase

Released:
Source organism: Homo sapiens
Primary publication:
Structure of the human dimeric ATM kinase.
OpenAccess logo Cell Cycle 15 1117-24 (2016)
PMID: 27097373
Related structures: EMD-6501

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-544997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase mTOR Chain: A
Molecule details ›
Chain: A
Length: 1165 amino acids
Theoretical weight: 133.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P42345 (Residues: 1385-2549; Coverage: 46%)
Gene names: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 28Å
Relevant EMDB volumes: EMD-6501
Expression system: Homo sapiens