› 3k4p

X-ray diffraction
2.4Å resolution

Aspergillus niger Phytase

Released:
DOI: 10.2210/pdb3k4p/pdb
PDB entry 3k4p coloured by chain, front view.
PDB entry 3k4p coloured by chain, side view.
PDB entry 3k4p coloured by chain, top view.
Source organism: Aspergillus niger
Primary publication:
The structure of Aspergillus niger phytase PhyA in complex with a phytate mimetic.
Oakley AJ
Biochem Biophys Res Commun 397 745-9 (2010)
PMID: 20541524

Function and Biology Details

Reaction catalysed: 
Myo-inositol hexakisphosphate + H(2)O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152723 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phytase A Chains: A, B
Molecule details ›
Chains: A, B
Length: 444 amino acids
Theoretical weight: 48.89 KDa
Source organism: Aspergillus niger
Expression system: Aspergillus niger
UniProt:
  • Canonical: P34752 (Residues: 24-467; Coverage: 100%)
Gene name: phyA
Sequence domains: Histidine phosphatase superfamily (branch 2)
Structure domains: Phosphoglycerate mutase-like

Ligands and Environments

1 bound ligand:
Ligand NAG 6 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 71.066Å b: 87.457Å c: 82.185Å
α: 90° β: 110.98° γ: 90°
R-values:
R R work R free
0.218 0.215 0.275
Expression system: Aspergillus niger

Quick links

Citations

2 review citations

Bioprocess for Production, Characteristics, and Biotechnological Applications of Fungal Phytases.
Jatuwong et al. (2020)
1 more

5 mentions without citation

Synthesis, Antimicrobial Screening, Homology Modeling, and Molecular Docking Studies of a New Series of Schiff Base Derivatives as Prospective Fungal Inhibitor Candidates.
Toubi et al. (2019)
4 more