› 3mi7

X-ray diffraction
2.2Å resolution

An Enhanced Repressor of Human Papillomavirus E2 Protein

Released:
DOI: 10.2210/pdb3mi7/pdb
PDB entry 3mi7 coloured by chain, front view.
PDB entry 3mi7 coloured by chain, side view.
PDB entry 3mi7 coloured by chain, top view.
Source organism: Human papillomavirus type 16
Primary publication:
Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Bose K, Meinke G, Bohm A, Baleja JD
FASEB J 25 2354-61 (2011)
PMID: 21482558

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136580 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein E2 Chain: X
Molecule details ›
Chain: X
Length: 85 amino acids
Theoretical weight: 9.78 KDa
Source organism: Human papillomavirus type 16
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03120 (Residues: 283-365; Coverage: 23%)
Gene name: E2
Sequence domains: E2 (early) protein, C terminal
Structure domains: Alpha-Beta Plaits

Ligands and Environments

1 bound ligand:
Ligand EDO 6 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: C2
Unit cell:
a: 59.86Å b: 43.099Å c: 45.666Å
α: 90° β: 120.53° γ: 90°
R-values:
R R work R free
0.188 0.184 0.281
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

[Fight against human papillomavirus - vaccinate or lotion?].
Zündorf I. (2011)

1 mention without citation

Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Bose et al. (2011)