› 3ov6

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151321 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-microglobulin; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1c Chain: A
Molecule details ›
Chain: A
Length: 397 amino acids
Theoretical weight: 44.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
  • Canonical: P29017 (Residues: 19-125, 127-204, 260-264; Coverage: 60%)
  • Canonical: P29016 (Residues: 126-126, 204-258, 264-295; Coverage: 28%)
Gene names: B2M, CD1B, CD1C, CDABP0092, HDCMA22P
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand NAG 1 x NAG
Ligand D12 1 x D12
Ligand MK0 1 x MK0
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 53.724Å b: 87.087Å c: 88.808Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.24 0.273
Expression system: Trichoplusia ni

Quick links

Citations

39 review citations

Recognition of CD1d-restricted antigens by natural killer T cells.
Rossjohn et al. (2012)
38 more

13 mentions without citation

The CD1 size problem: lipid antigens, ligands, and scaffolds.
Ly et al. (2014)
12 more