› 3tvt

X-ray diffraction
1.6Å resolution

Structural basis for Discs Large interaction with Pins

Released:
DOI: 10.2210/pdb3tvt/pdb
PDB entry 3tvt coloured by chain, front view.
PDB entry 3tvt coloured by chain, side view.
PDB entry 3tvt coloured by chain, top view.
Source organism: Drosophila melanogaster
Entry authors: Johnston CA, Doe CQ, Prehoda KE

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151871 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large 1 tumor suppressor protein Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 33.85 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31007 (Residues: 618-970; Coverage: 30%)
Gene names: CG1725, dlg1, l(1)dlg1
Sequence domains:
Structure domains:
Pins protein Chain: B
Molecule details ›
Chain: B
Length: 50 amino acids
Theoretical weight: 5.74 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9VB22 (Residues: 411-460; Coverage: 8%)
Gene names: CG5692, Dmel\CG5692, Dmel_CG5692, LGN, PINS, Pins, RAPS, Rad, Raps, dLGN, dPins, pins, pins/raps, rad, raps, rapsyn

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 91.604Å b: 94.546Å c: 83.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.22 0.245
Expression system: Escherichia coli BL21(DE3)

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