› 3vg0

X-ray diffraction
2.27Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213429 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Monoclonal antibody 9F8 Fab fragment L chain Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Monoclonal antibody 9F8 Fab fragment H chain Chain: H
Molecule details ›
Chain: H
Length: 223 amino acids
Theoretical weight: 23.81 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
2 bound ligands:
Ligand ACT 1 x ACT
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: C2
Unit cell:
a: 139.219Å b: 39.966Å c: 105.132Å
α: 90° β: 128.06° γ: 90°
R-values:
R R work R free
0.194 0.19 0.26

Quick links

Citations

10 review citations

The Leptin Receptor Complex: Heavier Than Expected?
Wauman et al. (2017)
9 more

1 mention without citation

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations.
Wong et al. (2022)