› 3w7y

X-ray diffraction
0.92Å resolution

0.92A structure of 2Zn human insulin at 100K

Released:
DOI: 10.2210/pdb3w7y/pdb
PDB entry 3w7y coloured by chain, front view.
PDB entry 3w7y coloured by chain, side view.
PDB entry 3w7y coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sakabe N, Sakabe K, Sasaki K, Murayoshi M

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134224 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6C
Spacegroup: R3
Unit cell:
a: 81.12Å b: 81.12Å c: 33.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.162 0.161 0.18

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