› 3wud

X-ray diffraction
1.68Å resolution

X-ray crystal structure of Xenopus laevis galectin-Ib

Released:
DOI: 10.2210/pdb3wud/pdb
PDB entry 3wud coloured by chain, front view.
PDB entry 3wud coloured by chain, side view.
PDB entry 3wud coloured by chain, top view.
Source organism: Xenopus laevis
Primary publication:
Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1.
Nonaka Y, Ogawa T, Yoshida H, Shoji H, Nishi N, Kamitori S, Nakamura T
Glycobiology 25 792-803 (2015)
PMID: 25804418

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin Chain: A
Molecule details ›
Chain: A
Length: 136 amino acids
Theoretical weight: 15.37 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q98UD4 (Residues: 1-134; Coverage: 100%)
Gene names: Galectin-Ia, lgals1, lgals1.1, lgals1.1.L, lgals1.L, xgalectin-Ib
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, GAL
Carbohydrate polymer
1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 67.21Å b: 35.32Å c: 58.51Å
α: 90° β: 111.82° γ: 90°
R-values:
R R work R free
0.2 0.197 0.253
Expression system: Escherichia coli

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Citations

1 review citation

Galectins in Protozoan Parasitic Diseases: Potential Applications in Diagnostics and Therapeutics.
Meira et al. (2023)
1 other article