› 3zcu

X-ray diffraction
2.05Å resolution

Rabbit muscle glycogen phosphorylase b in complex with N-(pyridyl-2- carbonyl)-N-beta-D-glucopyranosyl urea determined at 2.05 A resolution

Released:
DOI: 10.2210/pdb3zcu/pdb
PDB entry 3zcu coloured by chain, front view.
PDB entry 3zcu coloured by chain, side view.
PDB entry 3zcu coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Entry authors: Chrysina ED, Nagy V, Felfoldi N, Konya B, Telepo K, Praly JP, Docsa T, Gergely P, Alexacou KM, Hayes JM, Konstantakaki M, Kardakaris R, Leonidas DD, Zographos SE, Oikonomakos NG, Somsak L

Function and Biology Details

Reaction catalysed: 
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogen phosphorylase, muscle form Chain: A
Molecule details ›
Chain: A
Length: 843 amino acids
Theoretical weight: 97.42 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P00489 (Residues: 1-843; Coverage: 100%)
Gene name: PYGM
Sequence domains: Carbohydrate phosphorylase
Structure domains: Glycogen Phosphorylase B;

Ligands and Environments


Cofactor: Ligand PLP 1 x PLP
1 bound ligand:
Ligand T68 1 x T68
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P43212
Unit cell:
a: 128.414Å b: 128.414Å c: 116.523Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.216

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