› 3a4c

X-ray diffraction
1.89Å resolution

Crystal structure of cdt1 C terminal domain

Released:
DOI: 10.2210/pdb3a4c/pdb
PDB entry 3a4c coloured by chain, front view.
PDB entry 3a4c coloured by chain, side view.
PDB entry 3a4c coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of the Cdt1 C-terminal domain: conservation of the winged helix fold in replication licensing factors.
Khayrutdinov BI, Bae WJ, Yun YM, Lee JH, Tsuyama T, Kim JJ, Hwang E, Ryu KS, Cheong HK, Cheong C, Ko JS, Enomoto T, Karplus PA, Güntert P, Tada S, Jeon YH, Cho Y
Protein Sci 18 2252-64 (2009)
PMID: 19722278

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-569876 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA replication factor Cdt1 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 12.11 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8R4E9 (Residues: 452-557; Coverage: 19%)
Gene names: Cdt1, Ris2
Sequence domains: DNA replication factor Cdt1 C-terminal domain
Structure domains: DNA replication factor Cdt1, C-terminal WH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6C1
Spacegroup: P41212
Unit cell:
a: 52.565Å b: 52.565Å c: 96.035Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.236
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Chromosome Duplication in Saccharomyces cerevisiae.
Bell et al. (2016)
6 more

4 mentions without citation

Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability.
Pozo et al. (2016)
3 more