› 3av0

X-ray diffraction
3.1Å resolution

Crystal structure of Mre11-Rad50 bound to ATP S

Released:
DOI: 10.2210/pdb3av0/pdb
PDB entry 3av0 coloured by chain, front view.
PDB entry 3av0 coloured by chain, side view.
PDB entry 3av0 coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Entry authors: Lim HS, Kim JS, Cho Y

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176682 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA double-strand break repair protein Mre11 Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 45.37 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q58719 (Residues: 1-366; Coverage: 100%)
Gene names: MJ1323, mre11
Sequence domains:
Structure domains:
DNA double-strand break repair Rad50 ATPase Chain: B
Molecule details ›
Chain: B
Length: 371 amino acids
Theoretical weight: 42.39 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q58718 (Residues: 1-1005; Coverage: 37%)
Gene names: MJ1322, rad50
Sequence domains: AAA domain
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

5 bound ligands:
Ligand GOL 4 x GOL
Ligand IPA 3 x IPA
Ligand SO4 1 x SO4
Ligand AGS 1 x AGS
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: C2221
Unit cell:
a: 86.958Å b: 147.129Å c: 175.907Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.214 0.276
Expression system: Escherichia coli

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