› › Function and Biology

Functional analysis of hyperthermophilic endocellulase from the Archaeon Pyrococcus horikoshii

Source organism: Pyrococcus horikoshii OT3
Biochemical function: metal ion binding
Biological process: cellulose catabolic process
Cellular component: not assigned

Quick links

EC 3.2.1.4: Cellulase

Reaction catalysed:
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
Systematic name:
4-beta-D-glucan 4-glucanohydrolase
Alternative Name(s):
  • 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase
  • 9.5 cellulase
  • Alkali cellulase
  • Avicelase
  • Beta-1,4-endoglucan hydrolase
  • Beta-1,4-glucanase
  • Carboxymethyl cellulase
  • Celluase A
  • Celludextrinase
  • Cellulase A 3
  • Cellulosin AP
  • Endo-1,4-beta-D-glucanase
  • Endo-1,4-beta-D-glucanohydrolase
  • Endo-1,4-beta-glucanase
  • Endoglucanase
  • Endoglucanase D
  • Pancellase SS

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00150
Domain description: Cellulase (glycosyl hydrolase family 5)
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein
The deposited structure of PDB entry 3axx contains 3 copies of Pfam domain PF00150 (Cellulase (glycosyl hydrolase family 5)) in Glycoside hydrolase family 5 domain-containing protein. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR027552
Domain description: CGP-CTERM protein-sorting domain
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein
IPR018087
Domain description: Glycoside hydrolase, family 5, conserved site
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein
IPR001547
Domain description: Glycoside hydrolase, family 5
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein

Structure domain

CATH CATH domain
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Glycoside hydrolase family 5 domain-containing protein
The deposited structure of PDB entry 3axx contains 3 copies of CATH domain 3.20.20.80 (TIM Barrel) in Glycoside hydrolase family 5 domain-containing protein. Showing 1 copy in chain B.

Quick links