3bct › Citations

Three-dimensional structure of the armadillo repeat region of beta-catenin.

Huber AH, Nelson WJ, Weis WI
Cell 90 871-82 (1997)
Cited: 422 times
EuropePMC logo PMID: 9298899

Abstract

Beta-catenin is essential for cadherin-based cell adhesion and Wnt/Wingless growth factor signaling. In these roles, it binds to cadherins, Tcf-family transcription factors, and the tumor suppressor gene product Adenomatous Polyposis Coli (APC). A core region of beta-catenin, composed of 12 copies of a 42 amino acid sequence motif known as an armadillo repeat, mediates these interactions. The three-dimensional structure of a protease-resistant fragment of beta-catenin containing the armadillo repeat region has been determined. The 12 repeats form a superhelix of helices that features a long, positively charged groove. Although unrelated in sequence, the beta-catenin binding regions of cadherins, Tcfs, and APC are acidic and are proposed to interact with this groove.

Reviews - 3bct mentioned but not cited (3)

  1. Overview of protein structural and functional folds. Sun PD, Foster CE, Boyington JC. Curr Protoc Protein Sci Chapter 17 Unit 17.1 (2004)
  2. Recent developments of hybrid piezo-triboelectric nanogenerators for flexible sensors and energy harvesters. Zhang J, He Y, Boyer C, Kalantar-Zadeh K, Peng S, Chu D, Wang CH. Nanoscale Adv 3 5465-5486 (2021)
  3. The metaphorical swiss army knife: The multitude and diverse roles of HEAT domains in eukaryotic translation initiation. Friedrich D, Marintchev A, Arthanari H. Nucleic Acids Res 50 5424-5442 (2022)

Articles - 3bct mentioned but not cited (12)

  1. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard. Terwilliger TC, Adams PD, Read RJ, McCoy AJ, Moriarty NW, Grosse-Kunstleve RW, Afonine PV, Zwart PH, Hung LW. Acta Crystallogr. D Biol. Crystallogr. 65 582-601 (2009)
  2. Crystal structure of a full-length beta-catenin. Xing Y, Takemaru K, Liu J, Berndt JD, Zheng JJ, Moon RT, Xu W. Structure 16 478-487 (2008)
  3. Insights into Fanconi Anaemia from the structure of human FANCE. Nookala RK, Hussain S, Pellegrini L. Nucleic Acids Res. 35 1638-1648 (2007)
  4. Automatic multiple-zone rigid-body refinement with a large convergence radius. Afonine PV, Grosse-Kunstleve RW, Urzhumtsev A, Adams PD. J Appl Crystallogr 42 607-615 (2009)
  5. Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Han Y, Reyes AA, Malik S, He Y. Nature 579 452-455 (2020)
  6. Targeting the Epigenetic Non-Coding RNA MALAT1/Wnt Signaling Axis as a Therapeutic Approach to Suppress Stemness and Metastasis in Hepatocellular Carcinoma. Chang HL, Bamodu OA, Ong JR, Lee WH, Yeh CT, Tsai JT. Cells 9 E1020 (2020)
  7. Rapid model building of alpha-helices in electron-density maps. Terwilliger TC. Acta Crystallogr. D Biol. Crystallogr. 66 268-275 (2010)
  8. Molecular plasticity of beta-catenin: new insights from single-molecule measurements and MD simulation. Ritco-Vonsovici M, Ababou A, Horton M. Protein Sci. 16 1984-1998 (2007)
  9. Rapid chain tracing of polypeptide backbones in electron-density maps. Terwilliger TC. Acta Crystallogr. D Biol. Crystallogr. 66 285-294 (2010)
  10. The structural basis of urea-induced protein unfolding in β-catenin. Wang C, Chen Z, Hong X, Ning F, Liu H, Zang J, Yan X, Kemp J, Musselman CA, Kutateladze TG, Zhao R, Jiang C, Zhang G. Acta Crystallogr. D Biol. Crystallogr. 70 2840-2847 (2014)
  11. Rapid model building of beta-sheets in electron-density maps. Terwilliger TC. Acta Crystallogr. D Biol. Crystallogr. 66 276-284 (2010)
  12. Crystal structure of the Arabidopsis SPIRAL2 C-terminal domain reveals a p80-Katanin-like domain. Bolhuis DL, Dixit R, Slep KC. PLoS One 18 e0290024 (2023)


Reviews citing this publication (116)

  1. Wnt/β-catenin signaling and disease. Clevers H, Nusse R. Cell 149 1192-1205 (2012)
  2. Wnt signalling and its impact on development and cancer. Klaus A, Birchmeier W. Nat. Rev. Cancer 8 387-398 (2008)
  3. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Hartsock A, Nelson WJ. Biochim. Biophys. Acta 1778 660-669 (2008)
  4. beta-catenin signaling and cancer. Morin PJ. Bioessays 21 1021-1030 (1999)
  5. The many faces and functions of β-catenin. Valenta T, Hausmann G, Basler K. EMBO J. 31 2714-2736 (2012)
  6. Beta-catenin: a key mediator of Wnt signaling. Willert K, Nusse R. Curr. Opin. Genet. Dev. 8 95-102 (1998)
  7. Cadherins as modulators of cellular phenotype. Wheelock MJ, Johnson KR. Annu. Rev. Cell Dev. Biol. 19 207-235 (2003)
  8. beta-catenin destruction complex: insights and questions from a structural perspective. Kimelman D, Xu W. Oncogene 25 7482-7491 (2006)
  9. A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin. Willems AR, Schwab M, Tyers M. Biochim. Biophys. Acta 1695 133-170 (2004)
  10. Comparison of ARM and HEAT protein repeats. Andrade MA, Petosa C, O'Donoghue SI, Müller CW, Bork P. J. Mol. Biol. 309 1-18 (2001)
  11. The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin. Lilien J, Balsamo J. Curr. Opin. Cell Biol. 17 459-465 (2005)
  12. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Mosimann C, Hausmann G, Basler K. Nat. Rev. Mol. Cell Biol. 10 276-286 (2009)
  13. Signal transduction by the Wnt family of ligands. Dale TC. Biochem. J. 329 ( Pt 2) 209-223 (1998)
  14. Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer. Ben-Ze'ev A, Geiger B. Curr. Opin. Cell Biol. 10 629-639 (1998)
  15. Topological characteristics of helical repeat proteins. Groves MR, Barford D. Curr. Opin. Struct. Biol. 9 383-389 (1999)
  16. Biology of the adenomatous polyposis coli tumor suppressor. Goss KH, Groden J. J. Clin. Oncol. 18 1967-1979 (2000)
  17. The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation. Beavon IR. Eur. J. Cancer 36 1607-1620 (2000)
  18. Three decades of Wnts: a personal perspective on how a scientific field developed. Nusse R, Varmus H. EMBO J. 31 2670-2684 (2012)
  19. Wnt/beta-catenin signaling. Akiyama T. Cytokine Growth Factor Rev. 11 273-282 (2000)
  20. Structure and biochemistry of cadherins and catenins. Shapiro L, Weis WI. Cold Spring Harb Perspect Biol 1 a003053 (2009)
  21. When protein folding is simplified to protein coiling: the continuum of solenoid protein structures. Kobe B, Kajava AV. Trends Biochem. Sci. 25 509-515 (2000)
  22. Cytomechanics of cadherin-mediated cell-cell adhesion. Adams CL, Nelson WJ. Curr. Opin. Cell Biol. 10 572-577 (1998)
  23. Adhesion signaling: how beta-catenin interacts with its partners. Gottardi CJ, Gumbiner BM. Curr. Biol. 11 R792-4 (2001)
  24. The desmosome. Delva E, Tucker DK, Kowalczyk AP. Cold Spring Harb Perspect Biol 1 a002543 (2009)
  25. Phospho-regulation of Beta-catenin adhesion and signaling functions. Daugherty RL, Gottardi CJ. Physiology (Bethesda) 22 303-309 (2007)
  26. Drugging Wnt signalling in cancer. Polakis P. EMBO J. 31 2737-2746 (2012)
  27. Beta-catenin and Tcfs in mammary development and cancer. Hatsell S, Rowlands T, Hiremath M, Cowin P. J Mammary Gland Biol Neoplasia 8 145-158 (2003)
  28. Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. Verras M, Sun Z. Cancer Lett. 237 22-32 (2006)
  29. Transcription under the control of nuclear Arm/beta-catenin. Städeli R, Hoffmans R, Basler K. Curr. Biol. 16 R378-85 (2006)
  30. Control of beta-catenin signaling in tumor development. Behrens J. Ann N Y Acad Sci 910 21-33; discussion 33-5 (2000)
  31. Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis. Zámocký M, Koller F. Prog. Biophys. Mol. Biol. 72 19-66 (1999)
  32. The diversity of plant U-box E3 ubiquitin ligases: from upstream activators to downstream target substrates. Yee D, Goring DR. J. Exp. Bot. 60 1109-1121 (2009)
  33. Armadillo-repeat protein functions: questions for little creatures. Tewari R, Bailes E, Bunting KA, Coates JC. Trends Cell Biol. 20 470-481 (2010)
  34. Versatile TPR domains accommodate different modes of target protein recognition and function. Allan RK, Ratajczak T. Cell Stress Chaperones 16 353-367 (2011)
  35. VE-cadherin: adhesion at arm's length. Vincent PA, Xiao K, Buckley KM, Kowalczyk AP. Am. J. Physiol., Cell Physiol. 286 C987-97 (2004)
  36. Controversies at the cytoplasmic face of the cadherin-based adhesion complex. Provost E, Rimm DL. Curr. Opin. Cell Biol. 11 567-572 (1999)
  37. Plakophilins: Multifunctional proteins or just regulators of desmosomal adhesion? Hatzfeld M. Biochim. Biophys. Acta 1773 69-77 (2007)
  38. Wnt/beta-catenin signaling and small molecule inhibitors. Voronkov A, Krauss S. Curr. Pharm. Des. 19 634-664 (2013)
  39. WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Schmidt-Ott KM, Barasch J. Kidney Int. 74 1004-1008 (2008)
  40. The way Wnt works: components and mechanism. Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E. Growth Factors 31 1-31 (2013)
  41. Discovering the molecular components of intercellular junctions--a historical view. Franke WW. Cold Spring Harb Perspect Biol 1 a003061 (2009)
  42. The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets. Baarsma HA, Königshoff M, Gosens R. Pharmacol. Ther. 138 66-83 (2013)
  43. Regulation of Wnt/beta-catenin signaling by protein kinases. Verheyen EM, Gottardi CJ. Dev. Dyn. 239 34-44 (2010)
  44. The ENTH domain. De Camilli P, Chen H, Hyman J, Panepucci E, Bateman A, Brunger AT. FEBS Lett. 513 11-18 (2002)
  45. Wnt signaling: why is everything so negative? Brown JD, Moon RT. Curr. Opin. Cell Biol. 10 182-187 (1998)
  46. A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway. Phillips BT, Kimble J. Dev. Cell 17 27-34 (2009)
  47. Review: proteins with repeated sequence--structural prediction and modeling. Kajava AV. J. Struct. Biol. 134 132-144 (2001)
  48. Targeting the β-catenin nuclear transport pathway in cancer. Jamieson C, Sharma M, Henderson BR. Semin. Cancer Biol. 27 20-29 (2014)
  49. Kinesin motors and disease. Mandelkow E, Mandelkow EM. Trends Cell Biol. 12 585-591 (2002)
  50. The secret life of α-catenin: moonlighting in morphogenesis. Maiden SL, Hardin J. J. Cell Biol. 195 543-552 (2011)
  51. APC: the plot thickens. Bienz M. Curr. Opin. Genet. Dev. 9 595-603 (1999)
  52. The integration of cell adhesion with gene expression: the role of beta-catenin. Ben-Ze'ev A, Shtutman M, Zhurinsky J. Exp. Cell Res. 261 75-82 (2000)
  53. Ryanodine receptors: allosteric ion channel giants. Van Petegem F. J. Mol. Biol. 427 31-53 (2015)
  54. beta-catenin: molecular plasticity and drug design. Daniels DL, Eklof Spink K, Weis WI. Trends Biochem. Sci. 26 672-678 (2001)
  55. Desmosomal genodermatoses. Petrof G, Mellerio JE, McGrath JA. Br. J. Dermatol. 166 36-45 (2012)
  56. Modulation of Wnt signaling by Axin and Axil. Kikuchi A. Cytokine Growth Factor Rev. 10 255-265 (1999)
  57. The cytoplasmic face of cell contact sites. Pokutta S, Weis WI. Curr. Opin. Struct. Biol. 12 255-262 (2002)
  58. Aspects of the structure and assembly of desmosomes. Burdett ID. Micron 29 309-328 (1998)
  59. VHS domain -- a longshoreman of vesicle lines. Lohi O, Poussu A, Mao Y, Quiocho F, Lehto VP. FEBS Lett. 513 19-23 (2002)
  60. Diverse functions of p120ctn in tumors. van Hengel J, van Roy F. Biochim. Biophys. Acta 1773 78-88 (2007)
  61. Developmental functions of the P120-catenin sub-family. McCrea PD, Park JI. Biochim. Biophys. Acta 1773 17-33 (2007)
  62. The catenin family at a glance. McCrea PD, Gu D. J. Cell. Sci. 123 637-642 (2010)
  63. The dynamic role of beta-catenin in synaptic plasticity. Maguschak KA, Ressler KJ. Neuropharmacology 62 78-88 (2012)
  64. Desmosomes from a structural perspective. Stokes DL. Curr. Opin. Cell Biol. 19 565-571 (2007)
  65. Nucleic acid recognition by tandem helical repeats. Rubinson EH, Eichman BF. Curr. Opin. Struct. Biol. 22 101-109 (2012)
  66. Structural insights into clathrin-mediated endocytosis. Owen DJ, Luzio JP. Curr. Opin. Cell Biol. 12 467-474 (2000)
  67. Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease. Kang HS, ZeRuth G, Lichti-Kaiser K, Vasanth S, Yin Z, Kim YS, Jetten AM. Histol. Histopathol. 25 1481-1496 (2010)
  68. Turn up the HEAT. Kobe B, Gleichmann T, Horne J, Jennings IG, Scotney PD, Teh T. Structure 7 R91-7 (1999)
  69. Notch and Wnt signaling in the emergence of hematopoietic stem cells. Bigas A, Guiu J, Gama-Norton L. Blood Cells Mol. Dis. 51 264-270 (2013)
  70. The WNT/β-catenin dependent transcription: A tissue-specific business. Söderholm S, Cantù C. WIREs Mech Dis 13 e1511 (2021)
  71. Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer. Sabatino L, Pancione M, Votino C, Colangelo T, Lupo A, Novellino E, Lavecchia A, Colantuoni V. World J. Gastroenterol. 20 7137-7151 (2014)
  72. "Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases. Meirelles GV, Perez AM, de Souza EE, Basei FL, Papa PF, Melo Hanchuk TD, Cardoso VB, Kobarg J. World J Biol Chem 5 141-160 (2014)
  73. Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97. Ewens CA, Kloppsteck P, Förster A, Zhang X, Freemont PS. Biochem. Cell Biol. 88 41-48 (2010)
  74. Structural biology of cadherins in the nervous system. Shapiro L, Colman DR. Curr. Opin. Neurobiol. 8 593-599 (1998)
  75. Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling. Miller RK, Hong JY, Muñoz WA, McCrea PD. Prog Mol Biol Transl Sci 116 387-407 (2013)
  76. Modular peptide binding: from a comparison of natural binders to designed armadillo repeat proteins. Reichen C, Hansen S, Plückthun A. J. Struct. Biol. 185 147-162 (2014)
  77. Evolution and diversity of cadherins and catenins. Gul IS, Hulpiau P, Saeys Y, van Roy F. Exp. Cell Res. 358 3-9 (2017)
  78. Plakophilins in desmosomal adhesion and signaling. Hatzfeld M, Wolf A, Keil R. Cell Commun. Adhes. 21 25-42 (2014)
  79. Protein-protein interactions in intracellular membrane fusion. Misura KM, May AP, Weis WI. Curr. Opin. Struct. Biol. 10 662-671 (2000)
  80. VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases. Nakagawa T, Mondal K, Swanson PC. BMC Mol. Biol. 14 22 (2013)
  81. Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations. Mills RD, Mulhern TD, Cheng HC, Culvenor JG. Biochem. Soc. Trans. 40 1086-1089 (2012)
  82. Role of Aquaporin 1 Signalling in Cancer Development and Progression. Tomita Y, Dorward H, Yool AJ, Smith E, Townsend AR, Price TJ, Hardingham JE. Int J Mol Sci 18 (2017)
  83. Wingless/Wnt signaling in Drosophila: the pattern and the pathway. Bejsovec A. Mol. Reprod. Dev. 80 882-894 (2013)
  84. The role of adherens junctions in the developing neocortex. Stocker AM, Chenn A. Cell Adh Migr 9 167-174 (2015)
  85. Aptamers and their potential to selectively target aspects of EGF, Wnt/β-catenin and TGFβ-smad family signaling. Conidi A, van den Berghe V, Huylebroeck D. Int J Mol Sci 14 6690-6719 (2013)
  86. Genetics of primary macronodular adrenal hyperplasia. Fragoso MC, Alencar GA, Lerario AM, Bourdeau I, Almeida MQ, Mendonca BB, Lacroix A. J. Endocrinol. 224 R31-43 (2015)
  87. Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines. Clerico EM, Meng W, Pozhidaeva A, Bhasne K, Petridis C, Gierasch LM. Biochem J 476 1653-1677 (2019)
  88. Molecular structures of proteins involved in vesicle fusion. Ybe JA, Wakeham DE, Brodsky FM, Hwang PK. Traffic 1 474-479 (2000)
  89. Scaffolding for Repair: Understanding Molecular Functions of the SMC5/6 Complex. Diaz M, Pecinka A. Genes (Basel) 9 (2018)
  90. Discovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions. Yan M, Li G, An J. Exp. Biol. Med. (Maywood) 242 1185-1197 (2017)
  91. The multi-talented beta-catenin makes its first appearance. Shapiro L. Structure 5 1265-1268 (1997)
  92. Floppy but not sloppy: Interaction mechanism of FG-nucleoporins and nuclear transport receptors. Aramburu IV, Lemke EA. Semin. Cell Dev. Biol. 68 34-41 (2017)
  93. Overview of the Muscle Cytoskeleton. Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC. Compr Physiol 7 891-944 (2017)
  94. Role of Wnt signalling in early pregnancy. Nayeem SB, Arfuso F, Dharmarajan A, Keelan JA. Reprod Fertil Dev 28 525-544 (2016)
  95. News from the PUB: plant U-box type E3 ubiquitin ligases. Trujillo M. J. Exp. Bot. 69 371-384 (2018)
  96. Checking NEKs: Overcoming a Bottleneck in Human Diseases. Peres de Oliveira A, Kazuo Issayama L, Betim Pavan IC, Riback Silva F, Diniz Melo-Hanchuk T, Moreira Simabuco F, Kobarg J. Molecules 25 (2020)
  97. E3 Ubiquitin Ligase TRIP12: Regulation, Structure, and Physiopathological Functions. Brunet M, Vargas C, Larrieu D, Torrisani J, Dufresne M. Int J Mol Sci 21 E8515 (2020)
  98. Metabolic Contributions of Wnt Signaling: More Than Controlling Flight. Abou Azar F, Lim GE. Front Cell Dev Biol 9 709823 (2021)
  99. Multiple oncogenic roles of nuclear beta-catenin. Kumar R, Bashyam MD. J. Biosci. 42 695-707 (2017)
  100. Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis. Bejsovec A. Genetics 208 1311-1336 (2018)
  101. Wnt Signaling Polarizes C. elegans Asymmetric Cell Divisions During Development. Lam AK, Phillips BT. Results Probl Cell Differ 61 83-114 (2017)
  102. Βeta-catenin N-terminal domain: An enigmatic region prone to cancer causing mutations. Dar MS, Singh P, Mir RA, Dar MJ. Mutat. Res. 773 122-133 (2017)
  103. Adenomatous Polyposis Coli (APC) in cell migration. Fang X, Svitkina TM. Eur J Cell Biol 101 151228 (2022)
  104. Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk. Qin K, Yu M, Fan J, Wang H, Zhao P, Zhao G, Zeng W, Chen C, Wang Y, Wang A, Schwartz Z, Hong J, Song L, Wagstaff W, Haydon RC, Luu HH, Ho SH, Strelzow J, Reid RR, He TC, Shi LL. Genes Dis 11 103-134 (2024)
  105. Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature. Miroševič Š, Khandelwal S, Sušjan P, Žakelj N, Gosar D, Forstnerič V, Lainšček D, Jerala R, Osredkar D. Int J Mol Sci 23 12564 (2022)
  106. The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes. Nielsen MS, van Opbergen CJM, van Veen TAB, Delmar M. Physiol Rev 103 2271-2319 (2023)
  107. β-catenin inhibitors in cancer therapeutics: intricacies and way forward. Dev A, Vachher M, Prasad CP. Bioengineered 14 2251696 (2023)
  108. Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale. McCoy MA, Spicer D, Wells N, Hoogewijs K, Fiedler M, Baud MGJ. J Med Chem 65 7246-7261 (2022)
  109. Hallmark discoveries in the biology of Wilms tumour. Perotti D, Williams RD, Wegert J, Brzezinski J, Maschietto M, Ciceri S, Gisselsson D, Gadd S, Walz AL, Furtwaengler R, Drost J, Al-Saadi R, Evageliou N, Gooskens SL, Hong AL, Murphy AJ, Ortiz MV, O'Sullivan MJ, Mullen EA, van den Heuvel-Eibrink MM, Fernandez CV, Graf N, Grundy PE, Geller JI, Dome JS, Perlman EJ, Gessler M, Huff V, Pritchard-Jones K. Nat Rev Urol (2023)
  110. Intrinsically disordered proteins: modes of binding with emphasis on disordered domains. Morris OM, Torpey JH, Isaacson RL. Open Biol 11 210222 (2021)
  111. Targeting β-catenin in acute myeloid leukaemia: past, present, and future perspectives. Wagstaff M, Coke B, Hodgkiss GR, Morgan RG. Biosci Rep 42 BSR20211841 (2022)
  112. The Wnt-dependent and Wnt-independent functions of BCL9 in development, tumorigenesis, and immunity: Implications in therapeutic opportunities. Wu M, Dong H, Xu C, Sun M, Gao H, Bu F, Chen J. Genes Dis 11 701-710 (2024)
  113. Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer. Bian J, Dannappel M, Wan C, Firestein R. Cells 9 (2020)
  114. Understanding Arrhythmogenic Cardiomyopathy: Advances through the Use of Human Pluripotent Stem Cell Models. Chua CJ, Morrissette-McAlmon J, Tung L, Boheler KR. Genes (Basel) 14 1864 (2023)
  115. Wnt Signaling Inhibitors and Their Promising Role in Tumor Treatment. Pećina-Šlaus N, Aničić S, Bukovac A, Kafka A. Int J Mol Sci 24 6733 (2023)
  116. β-Catenin: oncogenic role and therapeutic target in cervical cancer. Wang B, Li X, Liu L, Wang M. Biol Res 53 33 (2020)

Articles citing this publication (291)

  1. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A. EMBO J. 17 1371-1384 (1998)
  2. The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. Das AK, Cohen PW, Barford D. EMBO J. 17 1192-1199 (1998)
  3. Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Conti E, Uy M, Leighton L, Blobel G, Kuriyan J. Cell 94 193-204 (1998)
  4. The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Huber AH, Weis WI. Cell 105 391-402 (2001)
  5. Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. Wu G, Xu G, Schulman BA, Jeffrey PD, Harper JW, Pavletich NP. Mol. Cell 11 1445-1456 (2003)
  6. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Kramps T, Peter O, Brunner E, Nellen D, Froesch B, Chatterjee S, Murone M, Züllig S, Basler K. Cell 109 47-60 (2002)
  7. Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Daniels DL, Weis WI. Nat. Struct. Mol. Biol. 12 364-371 (2005)
  8. Modular recognition of RNA by a human pumilio-homology domain. Wang X, McLachlan J, Zamore PD, Hall TM. Cell 110 501-512 (2002)
  9. PTEN-deficient intestinal stem cells initiate intestinal polyposis. He XC, Yin T, Grindley JC, Tian Q, Sato T, Tao WA, Dirisina R, Porter-Westpfahl KS, Hembree M, Johnson T, Wiedemann LM, Barrett TA, Hood L, Wu H, Li L. Nat. Genet. 39 189-198 (2007)
  10. Structural basis for sequence-specific recognition of DNA by TAL effectors. Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu JK, Shi Y, Yan N. Science 335 720-723 (2012)
  11. The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D. Cell 96 99-110 (1999)
  12. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B. Mol. Cell 27 262-274 (2007)
  13. Crystal structure of a beta-catenin/Tcf complex. Graham TA, Weaver C, Mao F, Kimelman D, Xu W. Cell 103 885-896 (2000)
  14. Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. Hamada K, Shimizu T, Matsui T, Tsukita S, Hakoshima T. EMBO J. 19 4449-4462 (2000)
  15. Structure of the protein phosphatase 2A holoenzyme. Xu Y, Xing Y, Chen Y, Chao Y, Lin Z, Fan E, Yu JW, Strack S, Jeffrey PD, Shi Y. Cell 127 1239-1251 (2006)
  16. Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Chook YM, Blobel G. Nature 399 230-237 (1999)
  17. Spotted leaf11, a negative regulator of plant cell death and defense, encodes a U-box/armadillo repeat protein endowed with E3 ubiquitin ligase activity. Zeng LR, Qu S, Bordeos A, Yang C, Baraoidan M, Yan H, Xie Q, Nahm BH, Leung H, Wang GL. Plant Cell 16 2795-2808 (2004)
  18. Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. Tago K, Nakamura T, Nishita M, Hyodo J, Nagai S, Murata Y, Adachi S, Ohwada S, Morishita Y, Shibuya H, Akiyama T. Genes Dev. 14 1741-1749 (2000)
  19. Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Ligon LA, Karki S, Tokito M, Holzbaur EL. Nat. Cell Biol. 3 913-917 (2001)
  20. Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells. Chen YT, Stewart DB, Nelson WJ. J. Cell Biol. 144 687-699 (1999)
  21. Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI. Mol. Cell 15 511-521 (2004)
  22. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Bosanac I, Alattia JR, Mal TK, Chan J, Talarico S, Tong FK, Tong KI, Yoshikawa F, Furuichi T, Iwai M, Michikawa T, Mikoshiba K, Ikura M. Nature 420 696-700 (2002)
  23. Regulation of beta-catenin structure and activity by tyrosine phosphorylation. Piedra J, Martinez D, Castano J, Miravet S, Dunach M, de Herreros AG. J. Biol. Chem. 276 20436-20443 (2001)
  24. Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Rose R, Weyand M, Lammers M, Ishizaki T, Ahmadian MR, Wittinghofer A. Nature 435 513-518 (2005)
  25. Crystal structure of a Pumilio homology domain. Wang X, Zamore PD, Hall TM. Mol. Cell 7 855-865 (2001)
  26. Structure of a mammalian ryanodine receptor. Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR. Nature 517 44-49 (2015)
  27. Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Ahmed Y, Hayashi S, Levine A, Wieschaus E. Cell 93 1171-1182 (1998)
  28. Structure of Pumilio reveals similarity between RNA and peptide binding motifs. Edwards TA, Pyle SE, Wharton RP, Aggarwal AK. Cell 105 281-289 (2001)
  29. Letter The ATRs, ATMs, and TORs are giant HEAT repeat proteins. Perry J, Kleckner N. Cell 112 151-155 (2003)
  30. Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Pan X, Roberts P, Chen Y, Kvam E, Shulga N, Huang K, Lemmon S, Goldfarb DS. Mol. Biol. Cell 11 2445-2457 (2000)
  31. Structure of the dimerization and beta-catenin-binding region of alpha-catenin. Pokutta S, Weis WI. Mol. Cell 5 533-543 (2000)
  32. beta-catenin can be transported into the nucleus in a Ran-unassisted manner. Yokoya F, Imamoto N, Tachibana T, Yoneda Y. Mol. Biol. Cell 10 1119-1131 (1999)
  33. Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker. ter Haar E, Musacchio A, Harrison SC, Kirchhausen T. Cell 95 563-573 (1998)
  34. beta-Catenin is a Nek2 substrate involved in centrosome separation. Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI. Genes Dev. 22 91-105 (2008)
  35. Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin. Liu J, Wang H, Zuo Y, Farmer SR. Mol. Cell. Biol. 26 5827-5837 (2006)
  36. Cell-autonomous beta-catenin signaling regulates cortical precursor proliferation. Woodhead GJ, Mutch CA, Olson EC, Chenn A. J. Neurosci. 26 12620-12630 (2006)
  37. Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis. Wong MH, Rubinfeld B, Gordon JI. J. Cell Biol. 141 765-777 (1998)
  38. Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin. Zhurinsky J, Shtutman M, Ben-Ze'ev A. Mol. Cell. Biol. 20 4238-4252 (2000)
  39. Homology-based method for identification of protein repeats using statistical significance estimates. Andrade MA, Ponting CP, Gibson TJ, Bork P. J. Mol. Biol. 298 521-537 (2000)
  40. Force-dependent conformational switch of α-catenin controls vinculin binding. Yao M, Qiu W, Liu R, Efremov AK, Cong P, Seddiki R, Payre M, Lim CT, Ladoux B, Mège RM, Yan J. Nat Commun 5 4525 (2014)
  41. Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase. Mossessova E, Gulbis JM, Goldberg J. Cell 92 415-423 (1998)
  42. Identification of a cellulose synthase-associated protein required for cellulose biosynthesis. Gu Y, Kaplinsky N, Bringmann M, Cobb A, Carroll A, Sampathkumar A, Baskin TI, Persson S, Somerville CR. Proc. Natl. Acad. Sci. U.S.A. 107 12866-12871 (2010)
  43. ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Daniels DL, Weis WI. Mol. Cell 10 573-584 (2002)
  44. Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Shomura Y, Dragovic Z, Chang HC, Tzvetkov N, Young JC, Brodsky JL, Guerriero V, Hartl FU, Bracher A. Mol. Cell 17 367-379 (2005)
  45. Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity. Choi HJ, Huber AH, Weis WI. J Biol Chem 281 1027-1038 (2006)
  46. Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Xing Y, Clements WK, Kimelman D, Xu W. Genes Dev. 17 2753-2764 (2003)
  47. Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF). Hyman J, Chen H, Di Fiore PP, De Camilli P, Brunger AT. J. Cell Biol. 149 537-546 (2000)
  48. Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ. Hum. Mol. Genet. 17 3105-3117 (2008)
  49. Structure of the Sec7 domain of the Arf exchange factor ARNO. Cherfils J, Ménétrey J, Mathieu M, Le Bras G, Robineau S, Béraud-Dufour S, Antonny B, Chardin P. Nature 392 101-105 (1998)
  50. Clathrin self-assembly is mediated by a tandemly repeated superhelix. Ybe JA, Brodsky FM, Hofmann K, Lin K, Liu SH, Chen L, Earnest TN, Fletterick RJ, Hwang PK. Nature 399 371-375 (1999)
  51. A chloroplast-localized PPR protein required for plastid ribosome accumulation. Williams PM, Barkan A. Plant J. 36 675-686 (2003)
  52. A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family. Mudgil Y, Shiu SH, Stone SL, Salt JN, Goring DR. Plant Physiol. 134 59-66 (2004)
  53. Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Mao Y, Nickitenko A, Duan X, Lloyd TE, Wu MN, Bellen H, Quiocho FA. Cell 100 447-456 (2000)
  54. The U-box protein family in plants. Azevedo C, Santos-Rosa MJ, Shirasu K. Trends Plant Sci. 6 354-358 (2001)
  55. CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes. Thompson BA, Tremblay V, Lin G, Bochar DA. Mol. Cell. Biol. 28 3894-3904 (2008)
  56. A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Chuang CF, Bargmann CI. Genes Dev. 19 270-281 (2005)
  57. Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription. Song LN, Herrell R, Byers S, Shah S, Wilson EM, Gelmann EP. Mol. Cell. Biol. 23 1674-1687 (2003)
  58. Gibberellins signal nuclear import of PHOR1, a photoperiod-responsive protein with homology to Drosophila armadillo. Amador V, Monte E, García-Martínez JL, Prat S. Cell 106 343-354 (2001)
  59. Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Katis VL, Lipp JJ, Imre R, Bogdanova A, Okaz E, Habermann B, Mechtler K, Nasmyth K, Zachariae W. Dev. Cell 18 397-409 (2010)
  60. Structural insights into RNA quality control: the Ro autoantigen binds misfolded RNAs via its central cavity. Stein AJ, Fuchs G, Fu C, Wolin SL, Reinisch KM. Cell 121 529-539 (2005)
  61. Crystal structure of the middle and C-terminal domains of the flagellar rotor protein FliG. Brown PN, Hill CP, Blair DF. EMBO J. 21 3225-3234 (2002)
  62. A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity. Mosher RA, Durrant WE, Wang D, Song J, Dong X. Plant Cell 18 1750-1765 (2006)
  63. Stability and folding of the tumour suppressor protein p16. Tang KS, Guralnick BJ, Wang WK, Fersht AR, Itzhaki LS. J. Mol. Biol. 285 1869-1886 (1999)
  64. Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Figueroa P, Gusmaroli G, Serino G, Habashi J, Ma L, Shen Y, Feng S, Bostick M, Callis J, Hellmann H, Deng XW. Plant Cell 17 1180-1195 (2005)
  65. Quantifying the similarities within fold space. Harrison A, Pearl F, Mott R, Thornton J, Orengo C. J. Mol. Biol. 323 909-926 (2002)
  66. A new Drosophila APC homologue associated with adhesive zones of epithelial cells. Yu X, Waltzer L, Bienz M. Nat Cell Biol 1 144-151 (1999)
  67. 2.8 A crystal structure of the malachite green aptamer. Baugh C, Grate D, Wilson C. J. Mol. Biol. 301 117-128 (2000)
  68. Crystal structure of a beta-catenin/BCL9/Tcf4 complex. Sampietro J, Dahlberg CL, Cho US, Hinds TR, Kimelman D, Xu W. Mol. Cell 24 293-300 (2006)
  69. Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching. Lee LK, Ginsburg MA, Crovace C, Donohoe M, Stock D. Nature 466 996-1000 (2010)
  70. Evolutionary specialization of the nuclear targeting apparatus. Malik HS, Eickbush TH, Goldfarb DS. Proc. Natl. Acad. Sci. U.S.A. 94 13738-13742 (1997)
  71. Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase. Yue WW, Hassler M, Roe SM, Thompson-Vale V, Pearl LH. EMBO J. 26 4402-4412 (2007)
  72. Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae. Hodel AE, Harreman MT, Pulliam KF, Harben ME, Holmes JS, Hodel MR, Berland KM, Corbett AH. J Biol Chem 281 23545-23556 (2006)
  73. Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription. Miravet S, Piedra J, Castaño J, Raurell I, Francí C, Duñach M, García de Herreros A. Mol. Cell. Biol. 23 7391-7402 (2003)
  74. Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro. Tutter AV, Fryer CJ, Jones KA. Genes Dev. 15 3342-3354 (2001)
  75. Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly. Rice LM, Brunger AT. Mol. Cell 4 85-95 (1999)
  76. Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. Eklof Spink K, Fridman SG, Weis WI. EMBO J. 20 6203-6212 (2001)
  77. Involvement of the tyrosine kinase fer in cell adhesion. Rosato R, Veltmaat JM, Groffen J, Heisterkamp N. Mol. Cell. Biol. 18 5762-5770 (1998)
  78. Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex. Nichols SA, Roberts BW, Richter DJ, Fairclough SR, King N. Proc. Natl. Acad. Sci. U.S.A. 109 13046-13051 (2012)
  79. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K. Genomics 74 234-244 (2001)
  80. An improved hydrogen bond potential: impact on medium resolution protein structures. Fabiola F, Bertram R, Korostelev A, Chapman MS. Protein Sci. 11 1415-1423 (2002)
  81. A single spacer nucleotide determines the specificities of two mRNA regulatory proteins. Opperman L, Hook B, DeFino M, Bernstein DS, Wickens M. Nat. Struct. Mol. Biol. 12 945-951 (2005)
  82. Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4. Hecht A, Stemmler MP. J. Biol. Chem. 278 3776-3785 (2003)
  83. Designed armadillo repeat proteins as general peptide-binding scaffolds: consensus design and computational optimization of the hydrophobic core. Parmeggiani F, Pellarin R, Larsen AP, Varadamsetty G, Stumpp MT, Zerbe O, Caflisch A, Plückthun A. J. Mol. Biol. 376 1282-1304 (2008)
  84. Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression. Prieve MG, Waterman ML. Mol. Cell. Biol. 19 4503-4515 (1999)
  85. Structure of the armadillo repeat domain of plakophilin 1. Choi HJ, Weis WI. J. Mol. Biol. 346 367-376 (2005)
  86. The Wnt /β-catenin signaling pathway in the adult neurogenesis. Zhang L, Yang X, Yang S, Zhang J. Eur. J. Neurosci. 33 1-8 (2011)
  87. A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. DasGupta R, Rhee H, Fuchs E. J. Cell Biol. 158 331-344 (2002)
  88. Plakoglobin regulates the expression of the anti-apoptotic protein BCL-2. Hakimelahi S, Parker HR, Gilchrist AJ, Barry M, Li Z, Bleackley RC, Pasdar M. J. Biol. Chem. 275 10905-10911 (2000)
  89. Roles of the C terminus of Armadillo in Wingless signaling in Drosophila. Cox RT, Pai LM, Kirkpatrick C, Stein J, Peifer M. Genetics 153 319-332 (1999)
  90. Structure of the human 26S proteasome: subunit radial displacements open the gate into the proteolytic core. da Fonseca PC, Morris EP. J. Biol. Chem. 283 23305-23314 (2008)
  91. A minimum folding unit in the ankyrin repeat protein p16(INK4). Zhang B, Peng Z. J. Mol. Biol. 299 1121-1132 (2000)
  92. The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells. de la Roche M, Worm J, Bienz M. BMC Cancer 8 199 (2008)
  93. The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity. Mi K, Dolan PJ, Johnson GV. J Biol Chem 281 4787-4794 (2006)
  94. Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion. Yang J, Dokurno P, Tonks NK, Barford D. EMBO J. 20 3645-3656 (2001)
  95. Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1. Prieve MG, Guttridge KL, Munguia J, Waterman ML. Mol. Cell. Biol. 18 4819-4832 (1998)
  96. New HEAT-like repeat motifs in proteins regulating proteasome structure and function. Kajava AV, Gorbea C, Ortega J, Rechsteiner M, Steven AC. J. Struct. Biol. 146 425-430 (2004)
  97. Structural insight into the rotational switching mechanism of the bacterial flagellar motor. Minamino T, Imada K, Kinoshita M, Nakamura S, Morimoto YV, Namba K. PLoS Biol. 9 e1000616 (2011)
  98. RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits. Jeronimo C, Langelier MF, Zeghouf M, Cojocaru M, Bergeron D, Baali D, Forget D, Mnaimneh S, Davierwala AP, Pootoolal J, Chandy M, Canadien V, Beattie BK, Richards DP, Workman JL, Hughes TR, Greenblatt J, Coulombe B. Mol. Cell. Biol. 24 7043-7058 (2004)
  99. A Drosophila APC tumour suppressor homologue functions in cellular adhesion. Hamada F, Bienz M. Nat. Cell Biol. 4 208-213 (2002)
  100. A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Yochum GS, Sherrick CM, Macpartlin M, Goodman RH. Proc. Natl. Acad. Sci. U.S.A. 107 145-150 (2010)
  101. A nuclear function for armadillo/beta-catenin. Tolwinski NS, Wieschaus E. PLoS Biol. 2 E95 (2004)
  102. Classification, expression pattern, and E3 ligase activity assay of rice U-box-containing proteins. Zeng LR, Park CH, Venu RC, Gough J, Wang GL. Mol Plant 1 800-815 (2008)
  103. A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress. Beck JR, Fung C, Straub KW, Coppens I, Vashisht AA, Wohlschlegel JA, Bradley PJ. PLoS Pathog. 9 e1003162 (2013)
  104. A comparative evaluation of beta-catenin and plakoglobin signaling activity. Williams BO, Barish GD, Klymkowsky MW, Varmus HE. Oncogene 19 5720-5728 (2000)
  105. Evolution of the metazoan-specific importin alpha gene family. Mason DA, Stage DE, Goldfarb DS. J. Mol. Evol. 68 351-365 (2009)
  106. Nuclear import: a tale of two sites. Dingwall C, Laskey RA. Curr. Biol. 8 R922-4 (1998)
  107. Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions. Gottardi CJ, Gumbiner BM. Am. J. Physiol., Cell Physiol. 286 C747-56 (2004)
  108. Characterization of Tbc2, a nucleus-encoded factor specifically required for translation of the chloroplast psbC mRNA in Chlamydomonas reinhardtii. Auchincloss AH, Zerges W, Perron K, Girard-Bascou J, Rochaix JD. J. Cell Biol. 157 953-962 (2002)
  109. Limits of cooperativity in a structurally modular protein: response of the Notch ankyrin domain to analogous alanine substitutions in each repeat. Bradley CM, Barrick D. J. Mol. Biol. 324 373-386 (2002)
  110. Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association. Gotter AL. J. Mol. Biol. 331 167-176 (2003)
  111. Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1. Dimitrova YN, Li J, Lee YT, Rios-Esteves J, Friedman DB, Choi HJ, Weis WI, Wang CY, Chazin WJ. J. Biol. Chem. 285 13507-13516 (2010)
  112. An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid. de la Roche M, Rutherford TJ, Gupta D, Veprintsev DB, Saxty B, Freund SM, Bienz M. Nat Commun 3 680 (2012)
  113. Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release. Fuerstenberg S, Peng CY, Alvarez-Ortiz P, Hor T, Doe CQ. Mol. Cell. Neurosci. 12 325-339 (1998)
  114. Specific armadillo repeat sequences facilitate β-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153, and RanBP2/Nup358. Sharma M, Jamieson C, Johnson M, Molloy MP, Henderson BR. J. Biol. Chem. 287 819-831 (2012)
  115. Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling. Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE. Mol. Biol. Cell 10 3151-3169 (1999)
  116. The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Jiang Y, Liu T, Lee CH, Chang Q, Yang J, Zhang Z. Nature 588 658-663 (2020)
  117. Cadherin sequences that inhibit beta-catenin signaling: a study in yeast and mammalian cells. Simcha I, Kirkpatrick C, Sadot E, Shtutman M, Polevoy G, Geiger B, Peifer M, Ben-Ze'ev A. Mol. Biol. Cell 12 1177-1188 (2001)
  118. Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes. Choi HJ, Gross JC, Pokutta S, Weis WI. J. Biol. Chem. 284 31776-31788 (2009)
  119. Identification of Tcf4 residues involved in high-affinity beta-catenin binding. Omer CA, Miller PJ, Diehl RE, Kral AM. Biochem. Biophys. Res. Commun. 256 584-590 (1999)
  120. LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin. Thyssen G, Li TH, Lehmann L, Zhuo M, Sharma M, Sun Z. Mol. Cell. Biol. 26 8857-8867 (2006)
  121. The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. Lee SJ, Imamoto N, Sakai H, Nakagawa A, Kose S, Koike M, Yamamoto M, Kumasaka T, Yoneda Y, Tsukihara T. J. Mol. Biol. 302 251-264 (2000)
  122. SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration. Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, Manik MK, Bosanac T, Landsberg MJ, Kerry PS, Mobli M, Hughes RO, Milbrandt J, Kobe B, DiAntonio A, Ve T. Neuron 109 1118-1136.e11 (2021)
  123. Target gene activation of the Wnt signaling pathway in nuclear beta-catenin accumulating cells of adamantinomatous craniopharyngiomas. Hölsken A, Kreutzer J, Hofmann BM, Hans V, Oppel F, Buchfelder M, Fahlbusch R, Blümcke I, Buslei R. Brain Pathol. 19 357-364 (2009)
  124. C-terminal armadillo repeats are essential and sufficient for association of the plant U-box armadillo E3 ubiquitin ligase SAUL1 with the plasma membrane. Drechsel G, Bergler J, Wippel K, Sauer N, Vogelmann K, Hoth S. J. Exp. Bot. 62 775-785 (2011)
  125. PECAM-1 promotes beta-catenin accumulation and stimulates endothelial cell proliferation. Biswas P, Canosa S, Schoenfeld J, Schoenfeld D, Tucker A, Madri JA. Biochem. Biophys. Res. Commun. 303 212-218 (2003)
  126. Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins. Suh EK, Gumbiner BM. Exp. Cell Res. 290 447-456 (2003)
  127. Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit. Au SW, Leng X, Harper JW, Barford D. J. Mol. Biol. 316 955-968 (2002)
  128. Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3. Nadolski MJ, Linder ME. J. Biol. Chem. 284 17720-17730 (2009)
  129. Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma brucei. McAllaster MR, Ikeda KN, Lozano-Núñez A, Anrather D, Unterwurzacher V, Gossenreiter T, Perry JA, Crickley R, Mercadante CJ, Vaughan S, de Graffenried CL. Mol. Biol. Cell 26 3013-3029 (2015)
  130. Thermodynamics of the high-affinity interaction of TCF4 with beta-catenin. Knapp S, Zamai M, Volpi D, Nardese V, Avanzi N, Breton J, Plyte S, Flocco M, Marconi M, Isacchi A, Caiolfa VR. J. Mol. Biol. 306 1179-1189 (2001)
  131. Crystal structure of transcription factor MalT domain III: a novel helix repeat fold implicated in regulated oligomerization. Steegborn C, Danot O, Huber R, Clausen T. Structure 9 1051-1060 (2001)
  132. The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. Braun JE, Tritschler F, Haas G, Igreja C, Truffault V, Weichenrieder O, Izaurralde E. EMBO J. 29 2368-2380 (2010)
  133. Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7. Pumroy RA, Ke S, Hart DJ, Zachariae U, Cingolani G. Structure 23 374-384 (2015)
  134. Structural basis of coactivation of liver receptor homolog-1 by β-catenin. Yumoto F, Nguyen P, Sablin EP, Baxter JD, Webb P, Fletterick RJ. Proc. Natl. Acad. Sci. U.S.A. 109 143-148 (2012)
  135. Early senescence and cell death in Arabidopsis saul1 mutants involves the PAD4-dependent salicylic acid pathway. Vogelmann K, Drechsel G, Bergler J, Subert C, Philippar K, Soll J, Engelmann JC, Engelsdorf T, Voll LM, Hoth S. Plant Physiol. 159 1477-1487 (2012)
  136. Is there a biological cost of protein disorder? Analysis of cancer-associated mutations. Pajkos M, Mészáros B, Simon I, Dosztányi Z. Mol Biosyst 8 296-307 (2012)
  137. N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways. Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y. Nat Commun 4 1589 (2013)
  138. Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1. Mbom BC, Siemers KA, Ostrowski MA, Nelson WJ, Barth AI. Mol. Biol. Cell 25 977-991 (2014)
  139. beta-Catenin shows an overlapping sequence requirement but distinct molecular interactions for its bidirectional passage through nuclear pores. Koike M, Kose S, Furuta M, Taniguchi N, Yokoya F, Yoneda Y, Imamoto N. J. Biol. Chem. 279 34038-34047 (2004)
  140. Analysis of beta-catenin aggregation and localization using GFP fusion proteins: nuclear import of alpha-catenin by the beta-catenin/Tcf complex. Giannini AL, Vivanco MM, Kypta RM. Exp. Cell Res. 255 207-220 (2000)
  141. E-cadherin polarity is determined by a multifunction motif mediating lateral membrane retention through ankyrin-G and apical-lateral transcytosis through clathrin. Jenkins PM, Vasavda C, Hostettler J, Davis JQ, Abdi K, Bennett V. J. Biol. Chem. 288 14018-14031 (2013)
  142. Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide. Dougherty PG, Wen J, Pan X, Koley A, Ren JG, Sahni A, Basu R, Salim H, Appiah Kubi G, Qian Z, Pei D. J Med Chem 62 10098-10107 (2019)
  143. Identification of an OPR protein involved in the translation initiation of the PsaB subunit of photosystem I. Rahire M, Laroche F, Cerutti L, Rochaix JD. Plant J. 72 652-661 (2012)
  144. Vac8p, an armadillo repeat protein, coordinates vacuole inheritance with multiple vacuolar processes. Tang F, Peng Y, Nau JJ, Kauffman EJ, Weisman LS. Traffic 7 1368-1377 (2006)
  145. Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons. März P, Probst A, Lang S, Schwager M, Rose-John S, Otten U, Ozbek S. J. Biol. Chem. 279 35542-35550 (2004)
  146. Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties. Garces RG, Gillon W, Pai EF. Protein Sci. 16 176-188 (2007)
  147. Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. An Y, Chen CY, Moyer B, Rotkiewicz P, Elsliger MA, Godzik A, Wilson IA, Balch WE. J. Mol. Biol. 391 26-41 (2009)
  148. The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway. Kim YS, Kang HS, Jetten AM. FEBS Lett. 581 858-864 (2007)
  149. Impaired sucrose induction1 encodes a conserved plant-specific protein that couples carbohydrate availability to gene expression and plant growth. Rook F, Corke F, Baier M, Holman R, May AG, Bevan MW. Plant J. 46 1045-1058 (2006)
  150. The roles of intrinsic disorder in orchestrating the Wnt-pathway. Xue B, Dunker AK, Uversky VN. J. Biomol. Struct. Dyn. 29 843-861 (2012)
  151. A novel protein RLS1 with NB-ARM domains is involved in chloroplast degradation during leaf senescence in rice. Jiao BB, Wang JJ, Zhu XD, Zeng LJ, Li Q, He ZH. Mol Plant 5 205-217 (2012)
  152. Fast and forceful refolding of stretched alpha-helical solenoid proteins. Kim M, Abdi K, Lee G, Rabbi M, Lee W, Yang M, Schofield CJ, Bennett V, Marszalek PE. Biophys. J. 98 3086-3092 (2010)
  153. Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Kirchner F, Schuetz A, Boldt LH, Martens K, Dittmar G, Haverkamp W, Thierfelder L, Heinemann U, Gerull B. Circ Cardiovasc Genet 5 400-411 (2012)
  154. Protein evolution: structure-function relationships of the oncogene beta-catenin in the evolution of multicellular animals. Schneider SQ, Finnerty JR, Martindale MQ. J. Exp. Zool. B Mol. Dev. Evol. 295 25-44 (2003)
  155. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Jabbour L, Welter JF, Kollar J, Hering TM. Genomics 81 292-303 (2003)
  156. The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target. Enzo MV, Rastrelli M, Rossi CR, Hladnik U, Segat D. Mol Cell Ther 3 1 (2015)
  157. Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation. Chen Y, Li Y, Xue J, Gong A, Yu G, Zhou A, Lin K, Zhang S, Zhang N, Gottardi CJ, Huang S. EMBO J. 35 668-684 (2016)
  158. Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-γ1 phosphorylation. Driessens G, Zheng Y, Locke F, Cannon JL, Gounari F, Gajewski TF. J. Immunol. 186 784-790 (2011)
  159. Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase. Díaz-Perales A, Quesada V, Sánchez LM, Ugalde AP, Suárez MF, Fueyo A, López-Otín C. J. Biol. Chem. 280 14310-14317 (2005)
  160. Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats. Dalhus B, Helle IH, Backe PH, Alseth I, Rognes T, Bjørås M, Laerdahl JK. Nucleic Acids Res. 35 2451-2459 (2007)
  161. F-actin organization and pollen tube tip growth in Arabidopsis are dependent on the gametophyte-specific Armadillo repeat protein ARO1. Gebert M, Dresselhaus T, Sprunck S. Plant Cell 20 2798-2814 (2008)
  162. The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. Straschil U, Talman AM, Ferguson DJ, Bunting KA, Xu Z, Bailes E, Sinden RE, Holder AA, Smith EF, Coates JC, Rita Tewari. PLoS ONE 5 e12901 (2010)
  163. Identification of the regions of PECAM-1 involved in beta- and gamma-catenin associations. Biswas P, Zhang J, Schoenfeld JD, Schoenfeld D, Gratzinger D, Canosa S, Madri JA. Biochem. Biophys. Res. Commun. 329 1225-1233 (2005)
  164. Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Traenkle B, Emele F, Anton R, Poetz O, Haeussler RS, Maier J, Kaiser PD, Scholz AM, Nueske S, Buchfellner A, Romer T, Rothbauer U. Mol. Cell Proteomics 14 707-723 (2015)
  165. Plakophilin, armadillo repeats, and nuclear localization. Klymkowsky MW. Microsc. Res. Tech. 45 43-54 (1999)
  166. The evolutionary origin of epithelial cell-cell adhesion mechanisms. Miller PW, Clarke DN, Weis WI, Lowe CJ, Nelson WJ. Curr Top Membr 72 267-311 (2013)
  167. Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor. Baker MA, Hynson RM, Ganuelas LA, Mohammadi NS, Liew CW, Rey AA, Duff AP, Whitten AE, Jeffries CM, Delalez NJ, Morimoto YV, Stock D, Armitage JP, Turberfield AJ, Namba K, Berry RM, Lee LK. Nat. Struct. Mol. Biol. 23 197-203 (2016)
  168. Identification of darlin, a Dictyostelium protein with Armadillo-like repeats that binds to small GTPases and is important for the proper aggregation of developing cells. Vithalani KK, Parent CA, Thorn EM, Penn M, Larochelle DA, Devreotes PN, De Lozanne A. Mol. Biol. Cell 9 3095-3106 (1998)
  169. X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster. Lee CF, Hauenstein AV, Fleming JK, Gasper WC, Engelke V, Sankaran B, Bernstein SI, Huxford T. Structure 19 397-408 (2011)
  170. Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila. Zhou MN, Kunttas-Tatli E, Zimmerman S, Zhouzheng F, McCartney BM. J. Cell. Sci. 124 1589-1600 (2011)
  171. Unusual armadillo fold in the human general vesicular transport factor p115. Striegl H, Roske Y, Kümmel D, Heinemann U. PLoS ONE 4 e4656 (2009)
  172. Wnt signaling: the good and the bad. Chen X, Yang J, Evans PM, Liu C. Acta Biochim. Biophys. Sin. (Shanghai) 40 577-594 (2008)
  173. Distinct and mutually inhibitory binding by two divergent β-catenins coordinates TCF levels and activity in C. elegans. Yang XD, Huang S, Lo MC, Mizumoto K, Sawa H, Xu W, Robertson S, Lin R. Development 138 4255-4265 (2011)
  174. ND9P, a novel protein with armadillo-like repeats involved in exocytosis: physiological studies using allelic mutants in paramecium. Froissard M, Keller AM, Cohen J. Genetics 157 611-620 (2001)
  175. Threonine 393 of beta-catenin regulates interaction with Axin. Wu H, Symes K, Seldin DC, Dominguez I. J. Cell. Biochem. 108 52-63 (2009)
  176. Complete functional segregation of planarian beta-catenin-1 and -2 in mediating Wnt signaling and cell adhesion. Chai G, Ma C, Bao K, Zheng L, Wang X, Sun Z, Salò E, Adell T, Wu W. J. Biol. Chem. 285 24120-24130 (2010)
  177. Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein. Tickenbrock L, Kössmeier K, Rehmann H, Herrmann C, Müller O. J. Mol. Biol. 327 359-367 (2003)
  178. Structural basis for the recognition of Asef by adenomatous polyposis coli. Zhang Z, Chen L, Gao L, Lin K, Zhu L, Lu Y, Shi X, Gao Y, Zhou J, Xu P, Zhang J, Wu G. Cell Res. 22 372-386 (2012)
  179. Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway. Mokhtarzada S, Yu C, Brickenden A, Choy WY. Biochemistry 50 715-726 (2011)
  180. The terminal region of beta-catenin promotes stability by shielding the Armadillo repeats from the axin-scaffold destruction complex. Mo R, Chew TL, Maher MT, Bellipanni G, Weinberg ES, Gottardi CJ. J. Biol. Chem. 284 28222-28231 (2009)
  181. Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes. Gerlach JP, Emmink BL, Nojima H, Kranenburg O, Maurice MM. Open Biol 4 140120 (2014)
  182. Biochemical and structural characterization of β-catenin interactions with nonphosphorylated and CK2-phosphorylated Lef-1. Sun J, Weis WI. J. Mol. Biol. 405 519-530 (2011)
  183. Mechanical properties of β-catenin revealed by single-molecule experiments. Valbuena A, Vera AM, Oroz J, Menéndez M, Carrión-Vázquez M. Biophys. J. 103 1744-1752 (2012)
  184. Comment Terminal regions of beta-catenin come into view. Gottardi CJ, Peifer M. Structure 16 336-338 (2008)
  185. A conserved phosphorylation switch controls the interaction between cadherin and β-catenin in vitro and in vivo. Choi HJ, Loveless T, Lynch AM, Bang I, Hardin J, Weis WI. Dev. Cell 33 82-93 (2015)
  186. Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8. Figueroa M, Hinrichs MV, Bunster M, Babbitt P, Martinez-Oyanedel J, Olate J. Protein Sci. 18 1139-1145 (2009)
  187. Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta. Stoothoff WH, Bailey CD, Mi K, Lin SC, Johnson GV. J. Neurochem. 83 904-913 (2002)
  188. Defining functional domains within PF16: a central apparatus component required for flagellar motility. Smith EF, Lefebvre PA. Cell Motil. Cytoskeleton 46 157-165 (2000)
  189. Mapping nucleolar localization sequences of 1A6/DRIM. Liu J, Du X, Ke Y. FEBS Lett. 580 1405-1410 (2006)
  190. Solution structure of a peptide derived from the oncogenic protein beta-Catenin in its phosphorylated and nonphosphorylated states. Megy S, Bertho G, Gharbi-Benarous J, Baleux F, Benarous R, Girault JP. Peptides 26 227-241 (2005)
  191. Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity. Cho K, Vaught TG, Ji H, Gu D, Papasakelariou-Yared C, Horstmann N, Jennings JM, Lee M, Sevilla LM, Kloc M, Reynolds AB, Watt FM, Brennan RG, Kowalczyk AP, McCrea PD. J. Cell. Sci. 123 4128-4144 (2010)
  192. cdk5 modulates beta- and delta-catenin/Pin1 interactions in neuronal cells. Muñoz JP, Huichalaf CH, Orellana D, Maccioni RB. J. Cell. Biochem. 100 738-749 (2007)
  193. Diverse LEA (late embryogenesis abundant) and LEA-like genes and their responses to hypersaline stress in post-diapause embryonic development of Artemia franciscana. Wu G, Zhang H, Sun J, Liu F, Ge X, Chen WH, Yu J, Wang W. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 160 32-39 (2011)
  194. Expression characteristics of β-catenin in scallop Chlamys farreri gonads and its role as a potential upstream gene of Dax1 through canonical Wnt signalling pathway regulating the spermatogenesis. Li H, Zhang Z, Bi Y, Yang D, Zhang L, Liu J. PLoS ONE 9 e115917 (2014)
  195. The armadillo repeats of the Ufd4 ubiquitin ligase recognize ubiquitin-fusion proteins. Ju D, Wang X, Xu H, Xie Y. FEBS Lett. 581 265-270 (2007)
  196. The interrelationship between DRIM gene expression and cytogenetic and phenotypic characteristics in human breast tumor cell lines. Goodison S, Viars C, Grazzini M, Urquidi V. BMC Genomics 4 39 (2003)
  197. bagpipe-Dependent expression of vimar, a novel Armadillo-repeats gene, in Drosophila visceral mesoderm. Lo PC, Frasch M. Mech. Dev. 72 65-75 (1998)
  198. Armadillo motifs involved in vesicular transport. Striegl H, Andrade-Navarro MA, Heinemann U. PLoS ONE 5 e8991 (2010)
  199. Letter The Drosophila clock protein Timeless is a member of the Arm/HEAT family. Vodovar N, Clayton JD, Costa R, Odell M, Kyriacou CP. Curr. Biol. 12 R610-1 (2002)
  200. ESA1 Is Involved in Embryo Sac Abortion in Interspecific Hybrid Progeny of Rice. Hou J, Hou J, Cao C, Ruan Y, Deng Y, Liu Y, Zhang K, Tan L, Zhu Z, Cai H, Liu F, Sun H, Gu P, Sun C, Fu Y. Plant Physiol 180 356-366 (2019)
  201. A small-molecule LF3 abrogates β-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes. Zhao L, Sun L, Lu Y, Li F, Xu H. J Mol Cell Cardiol 135 90-96 (2019)
  202. Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila. Cheng W, Ip YT, Xu Z. Gene 531 294-300 (2013)
  203. Parallel duplication and partial subfunctionalization of β-catenin/armadillo during insect evolution. Bao R, Fischer T, Bolognesi R, Brown SJ, Friedrich M. Mol. Biol. Evol. 29 647-662 (2012)
  204. RIFLE: a novel ring zinc finger-leucine-rich repeat containing protein, regulates select cell adhesion molecules in PC12 cells. Li B, Su Y, Ryder J, Yan L, Na S, Ni B. J. Cell. Biochem. 90 1224-1241 (2003)
  205. The PI(3)P interactome from a colon cancer cell. Catimel B, Kapp E, Yin MX, Gregory M, Wong LS, Condron M, Church N, Kershaw N, Holmes AB, Burgess AW. J Proteomics 82 35-51 (2013)
  206. The beta-catenin binding protein ICAT modulates androgen receptor activity. Zhuo M, Zhu C, Sun J, Weis WI, Sun Z. Mol. Endocrinol. 25 1677-1688 (2011)
  207. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, Qi S, Peng J, Hu B, Marcinkiewicz MM, Lamarre A, Wu J. Nat Commun 8 13834 (2017)
  208. Genome-wide survey of prokaryotic O-protein phosphatases. Bhaduri A, Sowdhamini R. J. Mol. Biol. 352 736-752 (2005)
  209. An E3 ubiquitin ligase, ERECT LEAF1, functions in brassinosteroid signaling of rice. Sakamoto T, Kitano H, Fujioka S. Plant Signal Behav 8 e27117 (2013)
  210. Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility. Zhang Z, Lin K, Gao L, Chen L, Shi X, Wu G. Biochem. Biophys. Res. Commun. 412 732-736 (2011)
  211. Emergent complexity in Myosin V-based organelle inheritance. Mast FD, Rachubinski RA, Dacks JB. Mol. Biol. Evol. 29 975-984 (2012)
  212. Kazrin, and its binding partners ARVCF- and delta-catenin, are required for Xenopus laevis craniofacial development. Cho K, Lee M, Gu D, Munoz WA, Ji H, Kloc M, McCrea PD. Dev. Dyn. 240 2601-2612 (2011)
  213. Identification of a novel role of ZMIZ2 protein in regulating the activity of the Wnt/β-catenin signaling pathway. Lee SH, Zhu C, Peng Y, Johnson DT, Lehmann L, Sun Z. J. Biol. Chem. 288 35913-35924 (2013)
  214. Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression. Götz R. Cancer Cell Int. 8 7 (2008)
  215. Metazoan evolution of the armadillo repeat superfamily. Gul IS, Hulpiau P, Saeys Y, van Roy F. Cell. Mol. Life Sci. 74 525-541 (2017)
  216. Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. Maiden SL, Petrova YI, Gumbiner BM. PLoS ONE 11 e0148574 (2016)
  217. Plant microtubule cytoskeleton complexity: microtubule arrays as fractals. Gardiner J, Overall R, Marc J. J. Exp. Bot. 63 635-642 (2012)
  218. Sex chromosome evolution in snakes inferred from divergence patterns of two gametologous genes and chromosome distribution of sex chromosome-linked repetitive sequences. Matsubara K, Nishida C, Matsuda Y, Kumazawa Y. Zoological Lett 2 19 (2016)
  219. Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2. Koutras C, Lévesque G. PLoS ONE 6 e25379 (2011)
  220. Solution structure of the epsin N-terminal homology (ENTH) domain of human epsin. Koshiba S, Kigawa T, Kikuchi A, Yokoyama S. J. Struct. Funct. Genomics 2 1-8 (2002)
  221. The U-box family genes in Medicago truncatula: Key elements in response to salt, cold, and drought stresses. Song J, Mo X, Yang H, Yue L, Song J, Mo B. PLoS ONE 12 e0182402 (2017)
  222. Wnt signaling: the β-cat(enin)'s meow. Bauer M, Willert K. Genes Dev. 26 105-109 (2012)
  223. Molecular characterization of an elicitor-responsive Armadillo repeat gene (GhARM) from cotton (Gossypium hirsutum). Phillips SM, Dubery IA, van Heerden H. Mol. Biol. Rep. 39 8513-8523 (2012)
  224. Our evolving view of Wnt signaling in C. elegans: If two's company and three's a crowd, is four really necessary? Robertson SM, Lin R. Worm 1 82-89 (2012)
  225. Physical characterization of plakophilin 1 reconstituted with and without zinc. Hofmann I, Mücke N, Reed J, Herrmann H, Langowski J. Eur. J. Biochem. 267 4381-4389 (2000)
  226. STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody. Megy S, Bertho G, Gharbi-Benarous J, Baleux F, Benarous R, Girault JP. FEBS Lett. 580 5411-5422 (2006)
  227. Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α. Ganesh K, van Maldegem F, Telerman SB, Simpson P, Johnson CM, Williams RL, Neuberger MS, Rada C. FEBS Lett. 588 21-27 (2014)
  228. The Arabidopsis paralogs, PUB46 and PUB48, encoding U-box E3 ubiquitin ligases, are essential for plant response to drought stress. Adler G, Konrad Z, Zamir L, Mishra AK, Raveh D, Bar-Zvi D. BMC Plant Biol. 17 8 (2017)
  229. Comparative Study The alpha and beta of turning on a molecular switch. Pai EF. Nat. Struct. Biol. 5 259-263 (1998)
  230. The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Huang X, Wang G, Wu Y, Du Z. Acta Crystallogr. D Biol. Crystallogr. 69 1598-1608 (2013)
  231. A Novel RHS1 Locus in Rice Attributes Seed-Pod Shattering by the Regulation of Endogenous S-Nitrosothiols. Mun BG, Shahid M, Lee GS, Hussain A, Yun BW. Int J Mol Sci 23 13225 (2022)
  232. Advanced glycation end products induce endothelial hyperpermeability via β-catenin phosphorylation and subsequent up-regulation of ADAM10. Weng J, Chen Z, Li J, He Q, Chen D, Yang L, Su H, Huang J, Yu S, Huang Q, Xu Q, Guo X. J Cell Mol Med 25 7746-7759 (2021)
  233. Dynamic Expression Profiles of β-Catenin during Murine Cardiac Valve Development. Guo L, Glover J, Risner A, Wang C, Fulmer D, Moore K, Gensemer C, Rumph MK, Moore R, Beck T, Norris RA. J Cardiovasc Dev Dis 7 E31 (2020)
  234. Evidence for the Nucleo-Apical Shuttling of a Beta-Catenin Like Plasmodium falciparum Armadillo Repeat Containing Protein. Mitra P, Gupta ED, Sahar T, Pandey AK, Dangi P, Reddy KS, Chauhan VS, Gaur D. PLoS ONE 11 e0148446 (2016)
  235. Isolation and nucleotide sequence analysis of the of Rhinella arenarum β-catenin: an mRNA and protein expression study during the larval stages of the digestive tract development. Galetto CD, Izaguirre MF, Bessone V, Casco VH. Gene 511 256-264 (2012)
  236. LRRpredictor-A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an Ensemble of Classifiers. Martin EC, Sukarta OCA, Spiridon L, Grigore LG, Constantinescu V, Tacutu R, Goverse A, Petrescu AJ. Genes (Basel) 11 (2020)
  237. Molecular genetic analysis of consanguineous families with primary microcephaly identified pathogenic variants in the ASPM gene. Khan MA, Windpassinger C, Ali MZ, Zubair M, Gul H, Abbas S, Khan S, Badar M, Mohammad RM, Nawaz Z. J. Genet. 96 383-387 (2017)
  238. Parallel and Sequential Pathways of Molecular Recognition of a Tandem-Repeat Protein and Its Intrinsically Disordered Binding Partner. Smith BM, Rowling PJE, Dobson CM, Itzhaki LS. Biomolecules 11 827 (2021)
  239. Protein-protein interaction site mapping using NMR-detected mutational scanning. Baminger B, Ludwiczek ML, Kontaxis G, Knapp S, Konrat R. J. Biomol. NMR 38 133-137 (2007)
  240. Solubilisation of the armadillo-repeat protein β-catenin using a zwitterionic detergent allows resolution of phosphorylated forms by 2DE. Layton MJ, Church NL, Faux MC, Ji H, Goode RJ, Kapp EA, Burgess AW, Simpson RJ. Electrophoresis 33 1804-1813 (2012)
  241. Comment A partnership that delivers. Kosik KS. Nat. Med. 5 149-150 (1999)
  242. ALEX1 may be a novel biomarker for human cervical squamous cell carcinoma. Zeng F, Liao K, Wu J, Gao Y, Li H, Fan J, Zhang H, Li Y, Bai X, Liu G, Song F. Int J Clin Exp Pathol 8 9434-9439 (2015)
  243. Diffusion of a disordered protein on its folded ligand. Wiggers F, Wohl S, Dubovetskyi A, Rosenblum G, Zheng W, Hofmann H. Proc Natl Acad Sci U S A 118 e2106690118 (2021)
  244. Identification of clustered organellar short (cos) RNAs and of a conserved family of organellar RNA-binding proteins, the heptatricopeptide repeat proteins, in the malaria parasite. Hillebrand A, Matz JM, Almendinger M, Müller K, Matuschewski K, Schmitz-Linneweber C. Nucleic Acids Res. 46 10417-10431 (2018)
  245. Immunohistochemical study of the membrane skeletal protein, membrane protein palmitoylated 6 (MPP6), in the mouse small intestine. Kamijo A, Saitoh Y, Ohno N, Ohno S, Terada N. Histochem. Cell Biol. 145 81-92 (2016)
  246. Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin. Mishra J, Das JK, Kumar N. J. Biol. Chem. 292 16406-16419 (2017)
  247. Nanoparticles (NPs)-Meditated LncRNA AFAP1-AS1 Silencing to Block Wnt/β-Catenin Signaling Pathway for Synergistic Reversal of Radioresistance and Effective Cancer Radiotherapy. Bi Z, Li Q, Dinglin X, Xu Y, You K, Hong H, Hu Q, Zhang W, Li C, Tan Y, Xie N, Ren W, Li C, Liu Y, Hu H, Xu X, Yao H. Adv Sci (Weinh) 7 2000915 (2020)
  248. Structural overview and perspectives of the nuclear receptors, a major family as the direct targets for small-molecule drugs. Li F, Song C, Zhang Y, Wu D. Acta Biochim Biophys Sin (Shanghai) 54 12-24 (2022)
  249. Structure of the hypothetical protein Ton1535 from Thermococcus onnurineus NA1 reveals unique structural properties by a left-handed helical turn in normal α-solenoid protein. Jeong JH, Kim YS, Rojvirija C, Cha HJ, Kim YG, Ha SC. Proteins 82 1072-1078 (2014)
  250. Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex. Luan Q, Liu SL, Helgeson LA, Nolen BJ. EMBO J. 37 (2018)
  251. The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division. Stypulkowski E, Asangani IA, Witze ES. Sci Signal 11 (2018)
  252. The human GID complex engages two independent modules for substrate recruitment. Mohamed WI, Park SL, Rabl J, Leitner A, Boehringer D, Peter M. EMBO Rep 22 e52981 (2021)
  253. Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease. Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. JCI Insight 5 (2020)
  254. Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin. van der Wal T, van Amerongen R. Open Biol 10 200267 (2020)
  255. A new CUT&RUN low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/β-catenin tissue-specific genomic targets. Zambanini G, Nordin A, Jonasson M, Pagella P, Cantù C. Development 149 dev201124 (2022)
  256. A novel de novo truncating variant in a Hungarian patient with CTNNB1 neurodevelopmental disorder. Nagy N, Pál M, Nagy D, Bokor BA, Zimmermann A, Gellén B, Salamon A, Sztriha L, Klivényi P, Széll M. BMC Pediatr 24 47 (2024)
  257. ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans. Luo H, Lao L, Au KS, Northrup H, He X, Forget D, Gauthier MS, Coulombe B, Bourdeau I, Shi W, Gagliardi L, Fragoso MCBV, Peng J, Wu J. Genome Biol 25 19 (2024)
  258. ARMCX Family Gene Expression Analysis and Potential Prognostic Biomarkers for Prediction of Clinical Outcome in Patients with Gastric Carcinoma. Wang T, Zhong H, Qin Y, Wei W, Li Z, Huang M, Luo X. Biomed Res Int 2020 3575038 (2020)
  259. Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells. Ambrosi G, Voloshanenko O, Eckert AF, Kranz D, Nienhaus GU, Boutros M. Elife 11 e64498 (2022)
  260. Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs. Hughes SA, Wang F, Wang S, Kreutzberger MAB, Osinski T, Orlova A, Wall JS, Zuo X, Egelman EH, Conticello VP. Proc. Natl. Acad. Sci. U.S.A. 116 14456-14464 (2019)
  261. An ensemble of flexible conformations underlies mechanotransduction by the cadherin-catenin adhesion complex. Bush M, Alhanshali BM, Qian S, Stanley CB, Heller WT, Matsui T, Weiss TM, Nicholl ID, Walz T, Callaway DJE, Bu Z. Proc. Natl. Acad. Sci. U.S.A. 116 21545-21555 (2019)
  262. Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2. Martinez Marshall MN, Emmerstorfer-Augustin A, Leskoske KL, Zhang LH, Li B, Thorner J. Mol. Biol. Cell 30 1555-1574 (2019)
  263. Characterization and function of a β-catenin homolog from Litopenaeus vannamei in WSSV infection. Sun J, Ruan L, Zhou C, Shi H, Xu X. Dev. Comp. Immunol. 76 412-419 (2017)
  264. Crystal structures of Uso1 membrane tether reveal an alternative conformation in the globular head domain. Heo Y, Yoon HJ, Ko H, Jang S, Lee HH. Sci Rep 10 9544 (2020)
  265. Domain architecture of BAF250a reveals the ARID and ARM-repeat domains with implication in function and assembly of the BAF remodeling complex. Sandhya S, Maulik A, Giri M, Singh M. PLoS ONE 13 e0205267 (2018)
  266. Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism. Ali N, Nguyen CB, Chandrakesan P, Wolf RF, Qu D, May R, Goretsky T, Fazili J, Barrett TA, Li M, Huycke MM, Bronze MS, Houchen CW. Sci Rep 10 10578 (2020)
  267. ERECT LEAF1 suppresses jasmonic acid response in rice by decreasing OsWRKY4 stability. Sakamoto T, Kitano H, Fujioka S. Plant Signal Behav 14 1559578 (2019)
  268. Episignature Mapping of TRIP12 Provides Functional Insight into Clark-Baraitser Syndrome. van der Laan L, Rooney K, Alders M, Relator R, McConkey H, Kerkhof J, Levy MA, Lauffer P, Aerden M, Theunis M, Legius E, Tedder ML, Vissers LELM, Koene S, Ruivenkamp C, Hoffer MJV, Wieczorek D, Bramswig NC, Herget T, González VL, Santos-Simarro F, Tørring PM, Denomme-Pichon AS, Isidor B, Keren B, Julia S, Schaefer E, Francannet C, Maillard PY, Misra-Isrie M, Van Esch H, Mannens MMAM, Sadikovic B, van Haelst MM, Henneman P. Int J Mol Sci 23 13664 (2022)
  269. Exploring Protein Intrinsic Disorder with MobiDB. Monzon AM, Hatos A, Necci M, Piovesan D, Tosatto SCE. Methods Mol Biol 2141 127-143 (2020)
  270. Exploring the roles of ZmARM gene family in maize development and abiotic stress response. Yu Z, Sun X, Chen Z, Wang Q, Zhang C, Liu X, Wu W, Yin Y. PeerJ 11 e16254 (2023)
  271. Expression of Wnt signaling skeletal development genes in the cartilaginous fish, elephant shark (Callorhinchus milii). D'Souza DG, Rana K, Milley KM, MacLean HE, Zajac JD, Bell J, Brenner S, Venkatesh B, Richardson SJ, Danks JA. Gen. Comp. Endocrinol. 193 1-9 (2013)
  272. FMRP recruitment of β-catenin to the translation pre-initiation complex represses translation. Ehyai S, Miyake T, Williams D, Vinayak J, Bayfield MA, McDermott JC. EMBO Rep. 19 (2018)
  273. Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis. Liu Z, Wang L, Li Y, Zhu J, Li Z, Chen L, Li H, Shi T, Yao P, Bi Z, Sun C, Bai J, Zhang J, Liu Y. BMC Genomics 25 10 (2024)
  274. Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling. Hwang WY, Kostiuk V, González DP, Lusk CP, Khokha MK. Elife 11 e70495 (2022)
  275. Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure. Jeong H, Park J, Kim HI, Lee M, Ko YJ, Lee S, Jun Y, Lee C. Proc. Natl. Acad. Sci. U.S.A. 114 E4539-E4548 (2017)
  276. Multivalent Interaction of Beta-Catenin With its Intrinsically Disordered Binding Partner Adenomatous Polyposis Coli. Rowling PJE, Murton BL, Du Z, Itzhaki LS. Front Mol Biosci 9 896493 (2022)
  277. Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis. Ma L, Shen T, Peng H, Wu J, Wang W, Gao X. J Oncol 2022 2352360 (2022)
  278. Purification, crystallization and preliminary X-ray diffraction studies of the β-catenin homolog HMP-2 from Caenorhabditis elegans. Choi HJ, Weis WI. Acta Crystallogr F Struct Biol Commun 71 272-276 (2015)
  279. RETRACTED ARTICLE: Human MTERF3 crystal structure forms a left-handed superhelix. Kim DU, Cho SG, Kim KL, Cho HS. Mol. Cells (2011)
  280. Role of Armadillo repeat 2 and kinesin-II motor subunit Klp64D for wingless signaling in Drosophila. Vuong LT, Won JH, Nguyen MB, Choi KW. Sci Rep 10 13864 (2020)
  281. Rotational direction of flagellar motor from the conformation of FliG middle domain in marine Vibrio. Nishikino T, Hijikata A, Miyanoiri Y, Onoue Y, Kojima S, Shirai T, Homma M. Sci Rep 8 17793 (2018)
  282. Stress-regulated elements in Lotus spp., as a possible starting point to understand signalling networks and stress adaptation in legumes. Menéndez AB, Ruiz OA. PeerJ 9 e12110 (2021)
  283. Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane. Knop J, Lienemann T, El-Kilani H, Falke S, Krings C, Sindalovskaya M, Bergler J, Betzel C, Hoth S. Int J Mol Sci 22 9455 (2021)
  284. Structural insights into ORF10 recognition by ZYG11B. Zhang B, Li Y, Feng Q, Song L, Dong C, Yan X. Biochem Biophys Res Commun 616 14-18 (2022)
  285. Structural underpinnings of Ric8A function as a G-protein α-subunit chaperone and guanine-nucleotide exchange factor. Srivastava D, Gakhar L, Artemyev NO. Nat Commun 10 3084 (2019)
  286. Structure-based mutational analysis of ICAT residues mediating negative regulation of β-catenin co-transcriptional activity. Domingues MJ, Martinez-Sanz J, Papon L, Larue L, Mouawad L, Bonaventure J. PLoS ONE 12 e0172603 (2017)
  287. Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Zhan J, Lin D, Watson N, Esser L, Tang WK, Zhang A, Liu X, Hassan R, Gleinich A, Shajahan A, Azadi P, Pastan I, Xia D. Cancer Res Commun 3 175-191 (2023)
  288. Structures of designed armadillo repeat proteins binding to peptides fused to globular domains. Hansen S, Kiefer JD, Madhurantakam C, Mittl PRE, Plückthun A. Protein Sci. 26 1942-1952 (2017)
  289. The genetic architecture of Plakophilin 2 cardiomyopathy. Dries AM, Kirillova A, Reuter CM, Garcia J, Zouk H, Hawley M, Murray B, Tichnell C, Pilichou K, Protonotarios A, Medeiros-Domingo A, Kelly MA, Baras A, Ingles J, Semsarian C, Bauce B, Celeghin R, Basso C, Jongbloed JDH, Nussbaum RL, Funke B, Cerrone M, Mestroni L, Taylor MRG, Sinagra G, Merlo M, Saguner AM, Elliott PM, Syrris P, van Tintelen JP, Regeneron Genetics Center, James CA, Haggerty CM, Parikh VN. Genet Med 23 1961-1968 (2021)
  290. The structural biology of canonical Wnt signalling. Agostino M, Pohl SÖ. Biochem Soc Trans 48 1765-1780 (2020)
  291. VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry. Delgado-Bellido D, Zamudio-Martínez E, Fernández-Cortés M, Herrera-Campos AB, Olmedo-Pelayo J, Perez CJ, Expósito J, de Álava E, Amaral AT, Valle FO, Diaz AG, Oliver FJ. Cell Death Dis 14 135 (2023)


Quick links