3blg Citations

Structural basis of the Tanford transition of bovine beta-lactoglobulin.

Biochemistry 37 14014-23 (1998)
Related entries: 1bsy, 2blg

Cited: 205 times
EuropePMC logo PMID: 9760236

Abstract

The structures of the trigonal crystal form of bovine beta-lactoglobulin variant A at pH 6.2, 7.1, and 8.2 have been determined by X-ray diffraction methods at a resolution of 2.56, 2. 24, and 2.49 A, respectively. The corresponding values for R (Rfree) are 0.192 (0.240), 0.234 (0.279), and 0.232 (0.277). The C and N termini as well as two disulfide bonds are clearly defined in these models. The glutamate side chain of residue 89 is buried at pH 6.2 and becomes exposed at pH 7.1 and 8.2. This conformational change, involving the loop 85-90, provides a structural basis for a variety of pH-dependent chemical, physical, and spectroscopic phenomena, collectively known as the Tanford transition.

Reviews - 3blg mentioned but not cited (3)

  1. Overview of protein structural and functional folds. Sun PD, Foster CE, Boyington JC. Curr Protoc Protein Sci Chapter 17 Unit 17.1 (2004)
  2. Recent Advances in NMR Protein Structure Prediction with ROSETTA. Koehler Leman J, Künze G. Int J Mol Sci 24 7835 (2023)
  3. Thoroughly review the recent progresses in improving O/W interfacial properties of proteins through various strategies. Zhang H, Zhao X, Chen X, Xu X. Front Nutr 9 1043809 (2022)

Articles - 3blg mentioned but not cited (22)



Reviews citing this publication (19)

  1. Invited review: beta-lactoglobulin: binding properties, structure, and function. Kontopidis G, Holt C, Sawyer L. J Dairy Sci 87 785-796 (2004)
  2. The Poisson-Boltzmann equation for biomolecular electrostatics: a tool for structural biology. Fogolari F, Brigo A, Molinari H. J Mol Recognit 15 377-392 (2002)
  3. Hemoglobin and heme scavenging. Ascenzi P, Bocedi A, Visca P, Altruda F, Tolosano E, Beringhelli T, Fasano M. IUBMB Life 57 749-759 (2005)
  4. Intracellular pH sensors: design principles and functional significance. Srivastava J, Barber DL, Jacobson MP. Physiology (Bethesda) 22 30-39 (2007)
  5. Experimentally determined lipocalin structures. Flower DR. Biochim Biophys Acta 1482 46-56 (2000)
  6. Bovine β-lactoglobulin/fatty acid complexes: binding, structural, and biological properties. Le Maux S, Bouhallab S, Giblin L, Brodkorb A, Croguennec T. Dairy Sci Technol 94 409-426 (2014)
  7. Identifying and Visualizing Macromolecular Flexibility in Structural Biology. Palamini M, Canciani A, Forneris F. Front Mol Biosci 3 47 (2016)
  8. Understanding the fabric of protein crystals: computational classification of biological interfaces and crystal contacts. Capitani G, Duarte JM, Baskaran K, Bliven S, Somody JC. Bioinformatics 32 481-489 (2016)
  9. Development and Characterization of Whey Protein-Based Nano-Delivery Systems: A Review. Ha HK, Rankin SA, Lee MR, Lee WJ. Molecules 24 E3254 (2019)
  10. Impact of the environmental conditions and substrate pre-treatment on whey protein hydrolysis: A review. Cheison SC, Kulozik U. Crit Rev Food Sci Nutr 57 418-453 (2017)
  11. High pressure effects on allergen food proteins. Somkuti J, Smeller L. Biophys Chem 183 19-29 (2013)
  12. Interactions of Whey Proteins with Metal Ions. Rodzik A, Pomastowski P, Sagandykova GN, Buszewski B. Int J Mol Sci 21 E2156 (2020)
  13. Anticalins as an alternative to antibody technology. Schlehuber S, Skerra A. Expert Opin Biol Ther 5 1453-1462 (2005)
  14. Milk Protein Polymer and Its Application in Environmentally Safe Adhesives. Guo M, Wang G. Polymers (Basel) 8 E324 (2016)
  15. Effect of Protein Genotypes on Physicochemical Properties and Protein Functionality of Bovine Milk: A Review. Gai N, Uniacke-Lowe T, O'Regan J, Faulkner H, Kelly AL. Foods 10 2409 (2021)
  16. Engineering Allostery into Proteins. Gorman SD, D'Amico RN, Winston DS, Boehr DD. Adv Exp Med Biol 1163 359-384 (2019)
  17. Transient non-native helix formation during the folding of β-lactoglobulin. Ikeguchi M. Biomolecules 4 202-216 (2014)
  18. β-Lactoglobulin and Glycodelin: Two Sides of the Same Coin? Sawyer L. Front Physiol 12 678080 (2021)
  19. Loading efficacy and binding analysis of retinoids with milk proteins: a short review. Agudelo D, Bourassa P, Bariyanga J, Tajmir-Riahi HA. J Biomol Struct Dyn 36 4246-4254 (2018)

Articles citing this publication (161)



Related citations provided by authors (1)