Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Interleukin-4
- Immunoglobulin-like fold
- Fibronectin type III
- Fibronectin type III superfamily
- Four-helical cytokine-like, core
- Short hematopoietin receptor, family 2, conserved site
- Type I cytokine receptor, cytokine-binding domain
- Interleukin-13 receptor subunit alpha-1, Ig-like domain
4 more domains
Structure domain:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Interleukin-4 receptor-ligand type-2 complex (preferred)
PDBe Complex ID:
PDB-CPX-138512 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Interleukin-4
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin 4
Structure domains: Growth Hormone; Chain: A;
Length: 129 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P05112 (Residues: 25-153; Coverage: 100%)
Sequence domains: Interleukin 4
Structure domains: Growth Hormone; Chain: A;
Soluble interleukin-4 receptor subunit alpha
Molecule details ›
Chain: B
Length: 205 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Length: 205 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P24394 (Residues: 27-227; Coverage: 25%)
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Interleukin-13 receptor subunit alpha-1
