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Crystal Structure of RelB-RelE antitoxin-toxin complex from Methanococcus jannaschii

Source organism: Methanocaldococcus jannaschii DSM 2661
Biochemical function: nuclease activity
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF05016
Domain description: ParE toxin of type II toxin-antitoxin system, parDE
Occurring in:
  1. Toxin RelE3
The deposited structure of PDB entry 3bpq contains 2 copies of Pfam domain PF05016 (ParE toxin of type II toxin-antitoxin system, parDE) in Toxin RelE3. Showing 1 copy in chain D.

PF18506
Domain description: RelB Antitoxin
Occurring in:
  1. Antitoxin RelB3
The deposited structure of PDB entry 3bpq contains 2 copies of Pfam domain PF18506 (RelB Antitoxin alpha helical domain) in Antitoxin RelB3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR035093
Domain description: Toxin-antitoxin system, RelE/ParE toxin domain superfamily
Occurring in:
  1. Toxin RelE3
IPR007712
Domain description: Toxin-antitoxin system, RelE/ParE toxin family
Occurring in:
  1. Toxin RelE3

Structure domains

CATH CATH domains
3.30.2310.20
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: YaeB-like fold
Homology: RelE-like
Occurring in:
  1. Toxin RelE3
The deposited structure of PDB entry 3bpq contains 2 copies of CATH domain 3.30.2310.20 (YaeB-like fold) in Toxin RelE3. Showing 1 copy in chain D.
6.10.250.2100
Class: Special
Architecture: Helix non-globular
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Antitoxin RelB3
The deposited structure of PDB entry 3bpq contains 1 copy of CATH domain 6.10.250.2100 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Antitoxin RelB3. Showing 1 copy in chain A.

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