› 3cad

X-ray diffraction
2.6Å resolution

Crystal structure of Natural Killer Cell Receptor, Ly49G

Released:
DOI: 10.2210/pdb3cad/pdb
PDB entry 3cad coloured by chain, front view.
PDB entry 3cad coloured by chain, side view.
PDB entry 3cad coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
Deng L, Cho S, Malchiodi EL, Kerzic MC, Dam J, Mariuzza RA
J Biol Chem 283 16840-9 (2008)
PMID: 18426793

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-178801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell lectin-like receptor 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 125 amino acids
Theoretical weight: 14.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60654 (Residues: 156-280; Coverage: 45%)
Gene names: Klra7, Ly-49g, Ly49-g, Ly49g, Ly49g4
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 133.378Å b: 56.196Å c: 33.761Å
α: 90° β: 100.29° γ: 90°
R-values:
R R work R free
0.23 0.227 0.286
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.
Wieczorek et al. (2017)
12 more

2 mentions without citation

Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
Deng et al. (2008)
1 more